HoxC5 Antibody (1E10): sc-517171
- HoxC5 Antibody (1E10) is a mouse monoclonal IgG2a κ HoxC5 antibody provided at 100 µg/ml
- raised against amino acids 1-68 representing partial length HoxC5 of human origin
- recommended for detection of HoxC5 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HoxC5 Antibody (1E10). This work is in progress.
HoxC5 Antibody (1E10) is a mouse monoclonal IgG2a kappa light chain antibody that detects HoxC5 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-HoxC5 antibody (1E10) is available as the non-conjugated format. HoxC5 protein, also known as homeobox C5, CP11, HOX3, or HOX3D, is a crucial transcription factor composed of 222 amino acids that plays a significant role in embryonic development by regulating gene expression. HoxC5 is localized in the nucleus, where HoxC5 binds to specific DNA sequences, thereby influencing the transcription of target genes essential for establishing positional identities during development. HoxC5 involvement in intricate regulatory networks guides morphogenesis, as HoxC5 is part of a larger family of Hox genes located on chromosome 12, which harbors over 1,100 genes and is implicated in various skeletal deformities such as hypochondrogenesis and achondrogenesis. HoxC5 exists in multiple alternatively spliced isoforms, enhancing functional diversity and making HoxC5 a vital component in developmental processes that shape the organism.
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HoxC5 Antibody (1E10) References:
- Complete mutation analysis panel of the 39 human HOX genes. | Kosaki, K., et al. 2002. Teratology. 65: 50-62. PMID: 11857506
- The upstream region of the human homeobox gene HOX3D is a target for regulation by retinoic acid and HOX homeoproteins. | Arcioni, L., et al. 1992. EMBO J. 11: 265-77. PMID: 1346761
- Analysis of single nucleotide polymorphisms and haplotypes in HOXC gene cluster within susceptible region 12q13 of simple congenital heart disease. | Gong, LG., et al. 2005. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 22: 497-501. PMID: 16215934
- Nomenclature for human homeobox genes. | McAlpine, PJ. and Shows, TB. 1990. Genomics. 7: 460. PMID: 1973146
- The human HOX gene family. | Acampora, D., et al. 1989. Nucleic Acids Res. 17: 10385-402. PMID: 2574852
- The thyroid transcription factor-1 gene is a candidate target for regulation by Hox proteins. | Guazzi, S., et al. 1994. EMBO J. 13: 3339-47. PMID: 7913891
- Fine mapping of human HOX gene clusters. | Apiou, F., et al. 1996. Cytogenet Cell Genet. 73: 114-5. PMID: 8646877
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HoxC5 Antibody (1E10) | sc-517171 | 100 µg/ml | $322.00 |