hnRNP A2/B1 Antibody (E-2): sc-374052
- hnRNP A2/B1 Antibody (E-2) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 209-243 within an internal region of hnRNP A2/B1 of human origin
- recommended for detection of hnRNP A2/B1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine and porcine
- See hnRNP A2/B1 (B-7): sc-374053 for hnRNP A2/B1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for hnRNP A2/B1 Antibody (E-2) for WB and IHC(P) applications. This reagent is now offered in a bundle with hnRNP A2/B1 Antibody (E-2) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
hnRNP A2/B1 Antibody (E-2) is a mouse monoclonal IgG1 antibody that detects hnRNP A2/B1 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). hnRNP A2/B1 plays a crucial role in pre-mRNA processing and is essential for proper mRNA splicing, which is vital for gene expression and cellular function. hnRNP A2/B1 is primarily located in the nucleus, where hnRNP A2/B1 interacts with pre-mRNA and splicing factors, influencing splice site selection and ensuring mature mRNA production. The ability of hnRNP A2/B1 to shuttle between the nucleus and cytoplasm enables participation in mRNA transport and translation, highlighting hnRNP A2/B1′s importance in post-transcriptional regulation. hnRNP A2/B1 forms complexes with other hnRNP proteins, contributing to dynamic regulation of gene expression in response to cellular signals. The versatility of hnRNP A2/B1 in various cellular processes underscores hnRNP A2/B1′s significance in maintaining cellular homeostasis and potential implications in diseases associated with splicing dysregulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
hnRNP A2/B1 Antibody (E-2) | sc-374052 | 200 µg/ml | $316.00 | |||
hnRNP A2/B1 Antibody (E-2): m-IgGκ BP-HRP Bundle | sc-535376 | 200 µg Ab; 40 µg BP | $354.00 | |||
hnRNP A2/B1 (E-2) Neutralizing Peptide | sc-374052 P | 100 µg/0.5 ml | $68.00 |