HN1 Antibody (3G6): sc-517032

HN1 Antibody (3G6) is a mouse monoclonal IgG1 kappa light chain antibody that detects HN1 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-HN1 antibody (3G6) is available as the non-conjugated format. Hematological and neurological expressed 1 protein (HN1), also known as androgen-regulated protein 2 (ARM2), is a 154 amino acid member of the HN1 family, which plays a significant role in embryo development, particularly in hemopoietic and neurological systems formation. HN1 localizes primarily in the nucleus and expresses across various fetal and adult tissues, with highest expression levels in brain, colon, prostate, testis, thymus, skeletal muscle, peripheral blood cells, and placenta. HN1′s nuclear localization suggests potential regulatory functions in gene expression and cellular signaling pathways, crucial for proper cellular function and development. HN1 has been linked to processed pseudogenes in mouse, rat, and human genomes, indicating that HN1 and pseudogenes may represent a novel gene family with evolutionary significance. Three isoforms of HN1 exist due to alternative splicing events, contributing to diverse functional roles in various biological contexts.

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HN1 Antibody (3G6) References:

1. An integrated physical and gene map of human distal chromosome 17q24-proximal 17q25 encompassing multiple disease loci.  |  Kalikin, LM., et al. 1999. Genomics. 57: 36-42. PMID: 10191081
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.  |  Ko, MS., et al. 2000. Development. 127: 1737-49. PMID: 10725249
3. Studying genomes through the aeons: protein families, pseudogenes and proteome evolution.  |  Harrison, PM. and Gerstein, M. 2002. J Mol Biol. 318: 1155-74. PMID: 12083509
4. Cloning, expression and subcellular localization of HN1 and HN1L genes, as well as characterization of their orthologs, defining an evolutionarily conserved gene family.  |  Zhou, G., et al. 2004. Gene. 331: 115-23. PMID: 15094197
5. Beyond linker histones and high mobility group proteins: global profiling of perchloric acid soluble proteins.  |  Zougman, A. and Wiśniewski, JR. 2006. J Proteome Res. 5: 925-34. PMID: 16602700
6. The peculiar journey of a selfish chromosome: mouse t haplotypes and meiotic drive.  |  Silver, LM. 1993. Trends Genet. 9: 250-4. PMID: 8379001
7. Murine Hn1 on chromosome 11 is expressed in hemopoietic and brain tissues.  |  Tang, W., et al. 1997. Mamm Genome. 8: 695-6. PMID: 9271675

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HN1 Antibody (3G6) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-HN1 Antibody (3G6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HN1 Antibody (3G6) Specifications

Alternate Product Name: HN1

Product Clone Name: 3G6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-154

Epitope Target: HN1

Epitope Species: human

Product Reactivity/Detection: HN1

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for HN1 Antibody (3G6): N/A