HLA-DRβ Antibody (TDR 31.1): sc-53321

HLA-DRβ Antibody (TDR 31.1) is a mouse monoclonal IgG1 antibody that detects HLA-DRβ in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). HLA-DRβ is a critical component of the major histocompatibility complex (MHC) class II molecules, which play a vital role in the immune response by presenting processed antigens to CD4+ T helper cells. Anti-HLA-DRβ antibody (TDR 31.1) recognizes a protein essential for T cell activation and adaptive immune response orchestration. HLA-DRβ is primarily located on the surface of antigen-presenting cells, including B cells, dendritic cells, and macrophages, where HLA-DRβ facilitates foreign antigen recognition. The interaction between HLA-DRβ and T cell receptors is fundamental for initiating immune responses, making HLA-DRβ a key player in the body′s defense against pathogens. Additionally, polymorphisms in the HLA-DRβ gene can influence susceptibility to various autoimmune diseases, highlighting HLA-DRβ′s importance in both health and disease. HLA-DRβ monoclonal antibody (TDR 31.1) serves as an invaluable tool for researchers studying immune responses, antigen presentation, and genetic factors influencing autoimmune conditions.

The preferred HLA-DRβ antibody is HLA-DRβ Antibody (DA2): sc-53314.