HLA class I Antibody (MEM-147): sc-51672
- HLA class I Antibody (MEM-147) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against PHA-activated human peripheral blood lymphocytes
- recommended for detection of all classical HLA class I molecules in native cell-surface forms of human origin by WB (non-reducing), IP and FCM
- available conjugated to phycoerythrin for IF, IHC(P) and FCM
- See HLA class I (HP-1F7): sc-69892 for HLA class I antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HLA class I Antibody (MEM-147). This work is in progress.
HLA class I Antibody (MEM-147) is a mouse monoclonal IgG1 antibody engineered to recognize all classical human leukocyte antigen (HLA) class I molecules, also known as major histocompatibility complex (MHC) class I proteins. These proteins are primarily located on the surface of nearly all nucleated cells, where they are essential for presenting endogenous peptide antigens to cytotoxic T lymphocytes, thereby playing a pivotal role in immune surveillance and the identification of infected or malignant cells. The strategic cell-surface localization of HLA class I molecules facilitates the immune system′s ability to monitor cellular health and respond to potential threats effectively. Anti-HLA class I antibody (MEM-147) is raised against phytohemagglutinin (PHA)-activated human peripheral blood lymphocytes, ensuring affinity for native cell-surface forms of HLA class I proteins. HLA class I monoclonal antibody (MEM-147) is highly versatile, performing reliably in various applications including western blotting (WB) under non-reducing conditions, immunoprecipitation (IP), and flow cytometry (FCM) for the detection of HLA class I molecules of human origin. By targeting HLA class I, HLA class I monoclonal antibody (MEM-147) supports critical research in areas such as immune responses, autoimmunity, and transplant compatibility. Anti-HLA class I antibody (MEM-147) is recommended for both basic and clinical immunological studies, and enhances our understanding of antigen presentation and T cell activation mechanisms, underscoring its importance in advancing immunological research and therapeutic development.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HLA class I Antibody (MEM-147) | sc-51672 | 100 µg/ml | $322.00 | |||
HLA class I Antibody (MEM-147) PE | sc-51672 PE | 100 tests in 2 ml | $349.00 |