HL60 Antigen Antibody (IPO-M6): sc-59203

HL60 Antigen Antibody (IPO-M6) is a mouse monoclonal IgG1 antibody that detects HL60 Antigen of human origin by flow cytometry (FCM). Anti-HL60 Antigen antibody (IPO-M6) is available in both non-conjugated and various conjugated forms, including phycoerythrin (PE) and fluorescein isothiocyanate (FITC), providing flexibility for different experimental needs. HL60 Antigen is crucial as this protein is associated with the HL60 cell line, derived from a human promyelocytic leukemia patient and serves as a valuable model for studying leukemia and hematopoietic differentiation. Understanding HL60 Antigen structure is particularly important due to its role in cell signaling pathways that regulate cell proliferation and apoptosis, making this protein a significant target for therapeutic interventions in leukemia. HL60 cell line research helps investigate cancer development mechanisms and test potential treatments, highlighting HL60 Antigen′s relevance in both basic and applied biomedical research. HL60 Antigen monoclonal antibody (IPO-M6) enables researchers to effectively identify and analyze leukemic cells, contributing to advancements in cancer diagnostics and therapies.

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HL60 Antigen Antibody (IPO-M6) References:

1. HL60 cells halted in G1 or S phase differentiate normally.  |  Brown, G., et al. 2002. Exp Cell Res. 281: 28-38. PMID: 12441127
2. Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells.  |  Grebenová, D., et al. 2003. J Photochem Photobiol B. 69: 71-85. PMID: 12633980
3. Carbohydrate-dependent signaling from the phosphatidylglucoside-based microdomain induces granulocytic differentiation of HL60 cells.  |  Nagatsuka, Y., et al. 2003. Proc Natl Acad Sci U S A. 100: 7454-9. PMID: 12802014
4. Lipopolysaccharide from the periodontal pathogen Porphyromonas gingivalis prevents apoptosis of HL60-derived neutrophils in vitro.  |  Murray, DA. and Wilton, JM. 2003. Infect Immun. 71: 7232-5. PMID: 14638824
5. Retinoic acid treated HL60 cells express CEACAM1 (CD66a) and phagocytose Neisseria gonorrhoeae.  |  Pantelic, M., et al. 2004. FEMS Immunol Med Microbiol. 42: 261-6. PMID: 15364113
6. Activation of c-kit by stem cell factor induces radioresistance to apoptosis through ERK-dependent expression of survivin in HL60 cells.  |  Jalal Hosseinimehr, S., et al. 2004. J Radiat Res. 45: 557-61. PMID: 15635266
7. Involvement of proapoptotic Bcl-2 family members in terbinafine-induced mitochondrial dysfunction and apoptosis in HL60 cells.  |  Yang, KC., et al. 2006. Food Chem Toxicol. 44: 214-26. PMID: 16125830
8. Apoptotic activity of isomalabaricane triterpenes on human promyelocytic leukemia HL60 cells.  |  Liu, WK., et al. 2005. Cancer Lett. 230: 102-10. PMID: 16253766
9. Comprehensive analysis of monoclonal antibodies against detergent-insoluble membrane/lipid rafts of HL60 cells.  |  Yamazaki, Y., et al. 2006. J Immunol Methods. 311: 106-16. PMID: 16564536

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HL60 Antigen Antibody (IPO-M6) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-HL60 Antigen Antibody (IPO-M6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HL60 Antigen Antibody (IPO-M6) Specifications

Alternate Product Name: HL60 Antigen

Product Clone Name: IPO-M6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: HL60 Antigen

Epitope Species: human

Product Reactivity/Detection: HL60

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: FCM

Vialing Information: Each vial contains 200 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for HL60 Antigen Antibody (IPO-M6): FITC: Fluoroscein, PE: Phycoerythrin