Hep C cAg Antibody (1868): sc-69937
- Hep C cAg Antibody (1868) is a mouse monoclonal IgG1, cited in 2 publications, provided at 100 µg/ml
- raised against Hepatitis C virus
- recommended for detection of core antigen genotypes 1a, 1b and 2a of Hepatitis C virus origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Hep C cAg Antibody (1868). This work is in progress.
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Hep C cAg Antibody (1868) is a mouse monoclonal IgG1 antibody that detects Hep C cAg protein of the Hepatitis C virus by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Hep C cAg plays a crucial role in the life cycle of the hepatitis C virus as a structural protein that forms the viral capsid, encapsulating viral RNA and essential proteins. Hep C cAg is primarily located in the cytoplasm of infected hepatocytes, where viral particles assemble before release into the bloodstream. Anti-Hep C cAg antibody (1868) helps researchers understand viral dynamics within cells, enabling development of targeted therapies that disrupt viral life cycles and potentially reduce chronic hepatitis C infections, which can lead to severe liver diseases such as cirrhosis and hepatocellular carcinoma. Hep C cAg monoclonal antibody (1868) serves as an essential tool for studying hepatitis C virus and host cell interactions, providing valuable insights into viral pathogenesis and treatment development.
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Hep C cAg Antibody (1868) References:
- HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1. | Shin, JY., et al. 2005. Exp Mol Med. 37: 138-45. PMID: 15886528
- Interaction of HCV core protein with 14-3-3epsilon protein releases Bax to activate apoptosis. | Lee, SK., et al. 2007. Biochem Biophys Res Commun. 352: 756-62. PMID: 17141194
- Neurotoxic effects of the HCV core protein are mediated by sustained activation of ERK via TLR2 signaling. | Paulino, AD., et al. 2011. J Neurovirol. 17: 327-40. PMID: 21660601
- Inhibition of the HCV core protein on the immune response to HBV surface antigen and on HBV gene expression and replication in vivo. | Zhu, W., et al. 2012. PLoS One. 7: e45146. PMID: 23024803
- Assessment of total hepatitis C virus (HCV) core protein in HCV-related mixed cryoglobulinemia. | Russi, S., et al. 2014. Arthritis Res Ther. 16: R73. PMID: 24636026
- Role of the exogenous HCV core protein in the interaction of human hepatocyte proliferation and macrophage sub-populations. | Yao, Z., et al. 2014. PLoS One. 9: e108278. PMID: 25265479
- N-terminal HCV core protein fragment decreases 20S proteasome activity in the presence of PA28γ. | Zheng, Y., et al. 2019. Biochem Biophys Res Commun. 509: 590-595. PMID: 30602418
- lncRNA HULC facilitates efficient loading of HCV-core protein onto lipid droplets and subsequent virus-particle release. | Sharma, G., et al. 2019. Cell Microbiol. 21: e13086. PMID: 31290220
- Plasmonic nanoplatform for point-of-care testing trace HCV core protein. | Li, X., et al. 2020. Biosens Bioelectron. 147: 111488. PMID: 31350137
- Impact of IL28 Genotypes and Modeling the Interactions of HCV Core Protein on Treatment of Hepatitis C. | Hashempour, T., et al. 2020. Interdiscip Sci. 12: 424-437. PMID: 32656614
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hep C cAg Antibody (1868) | sc-69937 | 100 µg/ml | $322.00 |