Hep B sAg Antibody (HB3): sc-51608
- Hep B sAg Antibody (HB3) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against purified Hep B sAg isolated from plasma of HBV origin
- recommended for detection of subtypes ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq- of Hep B origin by IF
- See Hep B sAg (1023): sc-53299 for Hep B sAg antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Hep B sAg Antibody (HB3). This work is in progress.
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Hep B sAg Antibody (HB3) is a mouse monoclonal IgG1 antibody that detects Hep B sAg of Hepatitis B by immunofluorescence (IF). Hep B sAg is a crucial protein antigen produced by the Hepatitis B virus, which belongs to the Hepadnavirus family and causes significant liver inflammation, jaundice, and in severe cases, death. Hep B sAg presence in the bloodstream serves as one of the earliest indicators of Hepatitis B infection, appearing before clinical symptoms manifest. Early detection enables timely diagnosis and management of the disease, as Hepatitis B infection increases risk of developing hepatocellular carcinoma, with over 250 million people currently infected worldwide. HBx protein, encoded by one of four open reading frames in the virus′s partially double-stranded 3.2 kilobase DNA genome, influences viral replication and host immune response. Anti-Hep B sAg antibody (HB3) serves as an essential tool for researchers and clinicians studying Hepatitis B virus infections and liver health implications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Hep B sAg Antibody (HB3) References:
- Hepatitis B surface antigen in saliva of HB-SAg carriers. | Feinman, SV., et al. 1975. J Lab Clin Med. 85: 1042-8. PMID: 1169272
- Hepatitis B and the HB-SAg carrier. An outbreak related to sexual contact. | Wright, RA. 1975. JAMA. 232: 717-21. PMID: 1173169
- Hepatitis B surface antigen in late hepatitis B infection. | Zeng, DW., et al. 2015. J Med Virol. 87: 380-7. PMID: 25604455
- Clinical significance of hepatitis B surface antigen mutants. | Coppola, N., et al. 2015. World J Hepatol. 7: 2729-39. PMID: 26644816
- The role of quantitative hepatitis B surface antigen revisited. | Cornberg, M., et al. 2017. J Hepatol. 66: 398-411. PMID: 27575311
- Durability of Interferon-induced Hepatitis B Surface Antigen Seroclearance. | Wu, Y., et al. 2020. Clin Gastroenterol Hepatol. 18: 514-516.e2. PMID: 30981007
- Identification of lymphocytes in percutaneous liver biopsy cores. Different T:B cell ratio in HB sAg-positive and -negative hepatitis. | Miller, DJ., et al. 1977. Gastroenterology. 72: 1199-203. PMID: 323096
- Hepatitis B surface antigen impairs TLR4 signaling by upregulating A20 expression in monocytes. | Wang, C., et al. 2024. Microbiol Spectr. 12: e0090924. PMID: 39248482
- Immunogenicity of hybrid hepatitis B surface antigen particles. | Mancini, M., et al. 1994. Int Rev Immunol. 11: 143-51. PMID: 8046275
- Hepatitis B surface antigen variation and protective immunity. | Howard, CR. and Allison, LM. 1995. Intervirology. 38: 35-40. PMID: 8666522
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hep B sAg Antibody (HB3) | sc-51608 | 100 µg/ml | $316.00 |