Hep B sAg Antibody (86C): sc-57786

Hep B sAg Antibody (86C) is a mouse monoclonal IgG1 antibody that detects Hep B sAg protein of Hepatitis B by western blotting (WB). Hep B sAg is a crucial protein antigen produced by the Hepatitis B virus, which belongs to the Hepadnavirus family and causes significant liver inflammation, jaundice, and in severe cases, death. Hep B sAg presence in the bloodstream serves as one of the earliest indicators of Hepatitis B infection, appearing before clinical symptoms manifest. Early detection enables timely diagnosis and management of the disease, as Hepatitis B infection increases risk of developing hepatocellular carcinoma, with over 250 million people currently infected worldwide. HBx protein, encoded by one of four open reading frames in the virus′s partially double-stranded 3.2 kilobase DNA genome, plays a significant role in viral life cycle and pathogenesis, highlighting the importance of monitoring Hep B sAg levels. Anti-Hep B sAg antibody (86C) serves as an essential tool for researchers and clinicians studying and combating Hepatitis B virus infection.

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Hep B sAg Antibody (86C) References:

1. Production of hepatitis B surface antigen in transgenic plants for oral immunization.  |  Richter, LJ., et al. 2000. Nat Biotechnol. 18: 1167-71. PMID: 11062435
2. Enumeration of hepatitis B surface antigen-specific B lymphocytes in responder and non-responder normal individuals vaccinated with recombinant hepatitis B surface antigen.  |  Shokrgozar, MA. and Shokri, F. 2001. Immunology. 104: 75-9. PMID: 11576223
3. Quantitation of hepatitis B surface antigen by an automated chemiluminescent microparticle immunoassay.  |  Deguchi, M., et al. 2004. J Virol Methods. 115: 217-22. PMID: 14667538
4. Kidney transplantation from hepatitis B surface antigen-positive donors into hepatitis B surface antigen-positive recipients: preliminary findings.  |  Veroux, M., et al. 2005. Transplant Proc. 37: 2467-8. PMID: 16182711
5. Mapping of linear B-cell epitopes of hepatitis B surface antigen.  |  Coursaget, P., et al. 1991. Res Virol. 142: 461-7. PMID: 1725062
6. Glycoproteins of natural origin with an affinity for hepatitis B surface antigen.  |  Millman, I. and McMichael, JC. 1978. Infect Immun. 21: 879-85. PMID: 213390
7. Induction of IFN-γ cytokine response against hepatitis B surface antigen using melittin.  |  Dezfuli, HT., et al. 2014. Gastroenterol Hepatol Bed Bench. 7: 108-17. PMID: 24834302
8. Large-scale purification of hepatitis B surface antigen using affinity chromatography.  |  Neurath, AR., et al. 1978. Experientia. 34: 414-5. PMID: 631288
9. Detection of hepatitis B surface antigen using time-resolved fluoroimmunoassay.  |  Siitari, H., et al. 1983. Nature. 301: 258-60. PMID: 6337344
10. Liver transplantation in European patients with the hepatitis B surface antigen.  |  Samuel, D., et al. 1993. N Engl J Med. 329: 1842-7. PMID: 8247035

The preferred Hep B sAg antibody is Hep B sAg Antibody (1023): sc-53299.