Hep B cAg Antibody (C1): sc-52410

Hep B cAg Antibody (C1) is a mouse monoclonal IgG2a antibody that detects Hep B cAg protein of Hepatitis B by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Hep B cAg plays a crucial role in the life cycle of the Hepatitis B virus, encapsulating the viral genome and forming the core of the virus, which is essential for assembly and stability. Understanding Hep B cAg structure is vital because this knowledge aids in diagnosing Hepatitis B infection and provides insights into viral replication and pathogenesis mechanisms. Hep B cAg presence in serum indicates active viral replication, making anti-Hep B cAg antibody (C1) a key marker for monitoring disease progression and treatment efficacy. Hep B cAg expression primarily occurs in liver cells where viral replication takes place, and anti-Hep B cAg antibody (C1) detection helps assess viral load and host immune response. Hep B cAg monoclonal antibody (C1) serves as an invaluable tool for researchers and clinicians working to understand and combat Hepatitis B virus infections.

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Hep B cAg Antibody (C1) References:

1. Immunochemical and morphological studies of hepatitis B core antigen isolated from the nuclei of hepatocytes.  |  Budkowska, A. 1977. J Infect Dis. 135: 463-7. PMID: 15037
2. A bi-functional hepatitis B virus core antigen (HBcAg) chimera activates HBcAg-specific T cells and preS1-specific antibodies.  |  Malik, IR., et al. 2012. Scand J Infect Dis. 44: 55-9. PMID: 21933033
3. MxA inhibits hepatitis B virus replication by interaction with hepatitis B core antigen.  |  Li, N., et al. 2012. Hepatology. 56: 803-11. PMID: 22271421
4. High copy numbers and N terminal insertion position of influenza A M2E fused with hepatitis B core antigen enhanced immunogenicity.  |  Sun, X., et al. 2015. Biosci Trends. 9: 221-7. PMID: 26355223
5. Detection of antibodies against hepatitis B core antigen using the avidin-biotin system.  |  Korec, E., et al. 1989. J Virol Methods. 24: 321-6. PMID: 2668320
6. Endoplasmic Reticulum Aminopeptidase 1 Is Involved in Anti-viral Immune Response of Hepatitis B Virus by Trimming Hepatitis B Core Antigen to Generate 9-Mers Peptides.  |  Liu, H., et al. 2022. Front Microbiol. 13: 829241. PMID: 35602060
7. Hepatitis B core antigen immune complexes in the liver of hepatitis B patients.  |  Ray, MB., et al. 1979. Clin Exp Immunol. 37: 15-24. PMID: 385186
8. Membranous glomerulopathy associated with hepatitis B core antigen immune complexes in children.  |  Slusarczyk, J., et al. 1980. Am J Pathol. 98: 29-43. PMID: 7350816
9. Hepatitis B core antigen and antibody.  |  Hoofnagle, JW. 1976. Bibl Haematol. 42: 60-4. PMID: 786264
10. Spatial structure and insertion capacity of immunodominant region of hepatitis B core antigen.  |  Borisova, G., et al. 1996. Intervirology. 39: 16-22. PMID: 8957665

The preferred Hep B cAg antibody is Hep B cAg Antibody (C1-5): sc-23945.