Hep B cAg Antibody (10C6): sc-52408

Hep B cAg Antibody (10C6) is a mouse monoclonal IgG2b antibody that detects Hep B cAg of Hepatitis B by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Hep B cAg plays a crucial role in the life cycle of the Hepatitis B virus, as Hep B cAg encapsulates the viral genome and forms the core of the virus, which is essential for assembly and stability. Understanding the structure of Hep B cAg is vital because Hep B cAg not only protects the viral genetic material but also serves as a target for the host immune response. The presence of Hep B cAg in the serum can indicate active viral replication, making Hep B cAg a key marker for diagnosing and monitoring Hepatitis B infection. Hep B cAg is primarily expressed in liver cells, where the virus replicates, and detection can provide insights into the viral load and the effectiveness of antiviral therapies. Anti-Hep B cAg antibody (10C6) is an invaluable tool for researchers studying Hepatitis B virus dynamics and for developing strategies to combat this significant public health challenge.

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Hep B cAg Antibody (10C6) References:

1. Detection and precipitation of hepatitis B core antigen using a fusion bacteriophage.  |  Hasmoni, SS., et al. 2005. J Gen Appl Microbiol. 51: 125-31. PMID: 15942873
2. Hepatitis B core antigen expression pattern reflects the response to anti-viral treatment.  |  Uzun, Y., et al. 2006. J Gastroenterol Hepatol. 21: 977-81. PMID: 16724981
3. Lentiviral vector encoding ubiquitinated hepatitis B core antigen induces potent cellular immune responses and therapeutic immunity in HBV transgenic mice.  |  Dai, S., et al. 2016. Immunobiology. 221: 813-21. PMID: 26874581
4. Hepatitis B core antigen based novel vaccine against porcine epidemic diarrhea virus.  |  Gillam, F., et al. 2018. J Virol Methods. 253: 61-69. PMID: 29129402
5. A label-free and reagentless immunoelectrode for antibodies against hepatitis B core antigen (anti-HBc) detection.  |  Trindade, EKG. and Dutra, RF. 2018. Colloids Surf B Biointerfaces. 172: 272-279. PMID: 30173094
6. Epidemiology, risk factors, and molecular characterization of occult hepatitis B infection among anti-hepatitis B core antigen alone subjects.  |  Azarkar, Z., et al. 2019. J Med Virol. 91: 615-622. PMID: 30345529
7. Expression and purification of Hepatitis B virus core antigen using Escherichia coli and its utilization for the diagnosis of Hepatitis B virus infections.  |  El-Mowafy, M., et al. 2024. Biologicals. 85: 101726. PMID: 37979341
8. Clinical implications of hepatitis B virus core antigen-mediated immunopathologic T cell responses in chronic hepatitis B.  |  Wang, LT., et al. 2024. J Med Virol. 96: e29515. PMID: 38469923
9. Serodiagnosis of hepatitis B virus infection by antibody to core antigen.  |  Irwin, GR., et al. 1977. J Infect Dis. 136: 31-6. PMID: 560416
10. Hybrid hepatitis B virus core antigen as a vaccine carrier moiety: I. presentation of foreign epitopes.  |  Schödel, F., et al. 1996. J Biotechnol. 44: 91-6. PMID: 8717391

The preferred Hep B cAg antibody is Hep B cAg Antibody (C1-5): sc-23945.