Hen Egg Lysozyme Antibody (A00004.01) is a mouse monoclonal IgG2b antibody that detects Hen Egg Lysozyme in avian species through western blotting (WB). Hen Egg Lysozyme, also known as lysozyme C (chicken-type), is a member of the glycosyl hydrolase 22 family and plays a crucial role in the immune defense of avian species. Anti-Hen Egg Lysozyme antibody (A00004.01) targets a protein primarily located in the egg white, where Hen Egg Lysozyme serves as a natural antibacterial agent, cleaving the glycosidic bonds in the peptidoglycan layer of bacterial cell walls, thereby contributing to the protection of the developing embryo from bacterial infections. Beyond bacteriolytic activity, Hen Egg Lysozyme is also involved in various biological processes, including the modulation of immune responses and the enhancement of phagocytic activity in immune cells. Hen Egg Lysozyme′s presence in food products and pharmaceuticals highlights its importance not only in avian biology but also in human health, as Hen Egg Lysozyme is utilized for its preservative qualities and potential therapeutic benefits. Anti-Hen Egg Lysozyme antibody (A00004.01) serves as an essential tool for researchers studying avian immunology and the functional roles of lysozymes in various biological contexts.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Hen Egg Lysozyme Antibody (A00004.01) References:
- Amyloid protofilament formation of hen egg lysozyme in highly concentrated ethanol solution. | Goda, S., et al. 2000. Protein Sci. 9: 369-75. PMID: 10716189
- Mutant mouse lysozyme carrying a minimal T cell epitope of hen egg lysozyme evokes high autoantibody response. | Tsujihata, Y., et al. 2000. J Immunol. 165: 3606-11. PMID: 11034362
- Effective reduction of antigenicity of hen egg lysozyme by site-specific glycosylation. | Usui, M., et al. 2004. FEBS Lett. 557: 169-73. PMID: 14741362
- Induction of autoimmunity by immunization with hapten-modified hen egg lysozyme in hen egg lysozyme-transgenic mice. | Kang, HK., et al. 2006. Immunology. 117: 368-78. PMID: 16476056
- Characterization of amyloidogenesis of hen egg lysozyme in concentrated ethanol solution. | Holley, M., et al. 2008. Biochem Biophys Res Commun. 373: 164-8. PMID: 18558086
- Biophysical characterization of DNA and RNA aptamer interactions with hen egg lysozyme. | Potty, AS., et al. 2011. Int J Biol Macromol. 48: 392-7. PMID: 21167858
- Immunogenicity of Structurally Perturbed Hen Egg Lysozyme Adsorbed to Silicone Oil Microdroplets in Wild-Type and Transgenic Mouse Models. | Chisholm, CF., et al. 2017. J Pharm Sci. 106: 1519-1527. PMID: 28216023
- A method to induce hen egg lysozyme-specific humoral immune tolerance in mice by pre-exposition with the protein's oligomers. | Ohkuri, T., et al. 2019. Biochem Biophys Rep. 20: 100679. PMID: 31463374
- Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody. | Akiba, H., et al. 2019. Sci Rep. 9: 15481. PMID: 31664051
- Association of the anti-hen egg lysozyme antibody HyHEL-5 with avian species variant and mutant lysozymes. | Shick, KA., et al. 1997. Biochim Biophys Acta. 1340: 205-14. PMID: 9252107