Hen Egg Lysozyme Antibody (NYRHEL): sc-73295

Hen Egg Lysozyme Antibody (NYRHEL) is a mouse monoclonal IgG2b antibody that detects Hen Egg Lysozyme of chicken origin by western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). Anti-Hen Egg Lysozyme antibody (NYRHEL) is available in a non-conjugated form, specifically designed for applications requiring high specificity and sensitivity. Hen Egg Lysozyme, also known as lysozyme C (chicken-type), is a member of the glycosyl hydrolase 22 family and plays a crucial role in the innate immune response. Hen Egg Lysozyme is primarily located in the egg white, where this protein serves as a natural antibacterial agent, cleaving the glycosidic bonds in the peptidoglycan layer of bacterial cell walls, thereby contributing to the defense against microbial infections. Hen Egg Lysozyme in egg whites not only protects the developing embryo from pathogens but also has significant implications in food preservation and safety, as Hen Egg Lysozyme can inhibit the growth of spoilage bacteria. Hen Egg Lysozyme has been shown to possess immunomodulatory properties, enhancing the activity of immune cells such as monocytes and macrophages, which further underscores the importance in both health and disease contexts.

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Hen Egg Lysozyme Antibody (NYRHEL) References:

1. Comparison of the kinetics of S-S bond, secondary structure, and active site formation during refolding of reduced denatured hen egg white lysozyme.  |  Roux, P., et al. 1999. Protein Sci. 8: 2751-60. PMID: 10631992
2. Genetic evidence that antibacterial activity of lysozyme is independent of its catalytic function.  |  Ibrahim, HR., et al. 2001. FEBS Lett. 506: 27-32. PMID: 11591365
3. Lysozyme from the insect Ceratitis capitata eggs.  |  Fernandez-Sousa, JM., et al. 1977. Eur J Biochem. 72: 25-33. PMID: 12978
4. Hen egg white lysozyme as an inhibitor of mushroom tyrosinase.  |  Li, B., et al. 2006. FEBS Lett. 580: 1877-82. PMID: 16516893
5. Cell wall substrate specificity of six different lysozymes and lysozyme inhibitory activity of bacterial extracts.  |  Nakimbugwe, D., et al. 2006. FEMS Microbiol Lett. 259: 41-6. PMID: 16684100
6. Inactivation of gram-negative bacteria in milk and banana juice by hen egg white and lambda lysozyme under high hydrostatic pressure.  |  Nakimbugwe, D., et al. 2006. Int J Food Microbiol. 112: 19-25. PMID: 16843561
7. Molecular cloning of an invertebrate goose-type lysozyme gene from Chlamys farreri, and lytic activity of the recombinant protein.  |  Zhao, J., et al. 2007. Mol Immunol. 44: 1198-208. PMID: 16911829
8. Structure and evolution of the Ivy protein family, unexpected lysozyme inhibitors in Gram-negative bacteria.  |  Abergel, C., et al. 2007. Proc Natl Acad Sci U S A. 104: 6394-9. PMID: 17405861
9. Epitope-dependent thermodynamic signature of single-domain antibodies against hen egg lysozyme.  |  Akiba, H., et al. 2021. J Biochem. 170: 623-629. PMID: 34519785
10. Structural Analysis of Hen Egg Lysozyme Refolded after Denaturation at Acidic pH.  |  Oda, M., et al. 2022. Protein J. 41: 71-78. PMID: 35094218
11. Hen Egg Lysozyme Alleviates Static Mechanical Pain Via NRF1-Parkin-TACAN Signaling Axis in Sensory Neurons.  |  Zhang, XL., et al. 2022. Neuroscience. 502: 52-67. PMID: 35985504
12. Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.  |  Blake, CC., et al. 1965. Nature. 206: 757-61. PMID: 5891407

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Hen Egg Lysozyme Antibody (NYRHEL) has 3 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Hen Egg Lysozyme Antibody (NYRHEL) Specifications

Alternate Product Name: Hen Egg Lysozyme

Product Clone Name: NYRHEL

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b

Amino Acids:

Epitope Target: Hen Egg Lysozyme

Epitope Species: chicken

Product Reactivity/Detection: Hen Egg Lysozyme

Species Reactivity/Detection: chicken

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, ELISA

Vialing Information: Each vial contains 100 µg IgG_2b in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for Hen Egg Lysozyme Antibody (NYRHEL): N/A