HDHD3 Antibody (C-1): sc-377141
- HDHD3 Antibody (C-1) is a mouse monoclonal IgG1 κ HDHD3 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 31-69 within an internal region of HDHD3 of human origin
- HDHD3 Antibody (C-1) is recommended for detection of HDHD3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-HDHD3 Antibody (C-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for HDHD3 Antibody (C-1) for WB and IHC(P) applications. This reagent is now offered in a bundle with HDHD3 Antibody (C-1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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HDHD3 Antibody (C-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects HDHD3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). HDHD3 (C-1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. HDHD3, also known as haloacid dehalogenase-like hydrolase domain containing 3, consists of 251 amino acids and is a member of the HAD-like hydrolase superfamily, which is characterized by unique structural features that differentiate HDHD3 from the α/β hydrolase family. HDHD3 plays a crucial role in the hydrolysis of haloacids, which is important for various metabolic processes, including the detoxification of halogenated compounds. The HDHD3 gene is located on human chromosome 9q32, a region that comprises about 4% of the human genome and is involved in critical biological functions, including gender determination. Notably, deletions in this chromosomal region can lead to sex reversal phenotypes, highlighting HDHD3′s importance in developmental biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
HDHD3 Antibody (C-1) References:
- DNA sequence and analysis of human chromosome 9. | Humphray, SJ., et al. 2004. Nature. 429: 369-74. PMID: 15164053
- BCR-ABL activates STAT3 via JAK and MEK pathways in human cells. | Coppo, P., et al. 2006. Br J Haematol. 134: 171-9. PMID: 16846476
- BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility. | Zheng, X., et al. 2006. BMC Cancer. 6: 262. PMID: 17090304
- Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia. | Fernandez-L, A., et al. 2007. Hum Mol Genet. 16: 1515-33. PMID: 17420163
- Phenotypic and cytogenetic spectrum of 9p trisomy. | Temtamy, SA., et al. 2007. Genet Couns. 18: 29-48. PMID: 17515299
- Potential role of tubulin acetylation and microtubule-based protein trafficking in familial dysautonomia. | Gardiner, J., et al. 2007. Traffic. 8: 1145-9. PMID: 17605759
- Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease). | Cottin, V., et al. 2007. Respiration. 74: 361-78. PMID: 17641482
- A humanized IKBKAP transgenic mouse models a tissue-specific human splicing defect. | Hims, MM., et al. 2007. Genomics. 90: 389-96. PMID: 17644305
- Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia. | Burmeister, T., et al. 2007. Haematologica. 92: 1699-702. PMID: 18055996
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HDHD3 Antibody (C-1) | sc-377141 | 200 µg/ml | $322.00 | |||
HDHD3 Antibody (C-1): m-IgGκ BP-HRP Bundle | sc-523208 | 200 µg Ab, 40 µg BP | $361.00 | |||
HDHD3 Antibody (C-1) AC | sc-377141 AC | 500 µg/ml, 25% agarose | $424.00 | |||
HDHD3 Antibody (C-1) HRP | sc-377141 HRP | 200 µg/ml | $322.00 | |||
HDHD3 Antibody (C-1) FITC | sc-377141 FITC | 200 µg/ml | $336.00 | |||
HDHD3 Antibody (C-1) PE | sc-377141 PE | 200 µg/ml | $349.00 | |||
HDHD3 Antibody (C-1) Alexa Fluor® 488 | sc-377141 AF488 | 200 µg/ml | $364.00 | |||
HDHD3 Antibody (C-1) Alexa Fluor® 546 | sc-377141 AF546 | 200 µg/ml | $364.00 | |||
HDHD3 Antibody (C-1) Alexa Fluor® 594 | sc-377141 AF594 | 200 µg/ml | $364.00 | |||
HDHD3 Antibody (C-1) Alexa Fluor® 647 | sc-377141 AF647 | 200 µg/ml | $364.00 | |||
HDHD3 Antibody (C-1) Alexa Fluor® 680 | sc-377141 AF680 | 200 µg/ml | $364.00 | |||
HDHD3 Antibody (C-1) Alexa Fluor® 790 | sc-377141 AF790 | 200 µg/ml | $364.00 | |||
HDHD3 (C-1) Neutralizing Peptide | sc-377141 P | 100 µg/0.5 ml | $69.00 |