CD44 Antibody (OX49): sc-53068
- CD44 Antibody (OX49) is a mouse monoclonal IgG2a κ, cited in 6 publications, provided at 200 µg/ml
- raised against HCAM of rat origin
- recommended for detection of HCAM of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for CD44 Antibody (OX49) for WB and IHC(P) applications. These reagents are now offered in bundles with CD44 Antibody (OX49) (see ordering information below).
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HCAM Antibody (OX49) is a mouse monoclonal IgG2a antibody that detects HCAM in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). HCAM, also known as CD44, is a 742 amino acid single-pass type I membrane protein that plays a crucial role in cell adhesion and migration, which are vital processes in embryogenesis, immune response, and tumor metastasis. HCAM functions as a receptor for hyaluronic acid (HA) and interacts with ligands such as osteopontin (OPN), facilitating both cell-cell and cell-matrix interactions. HCAM′s structure features a Link domain, which is essential for binding capabilities, and undergoes alternative splicing, resulting in multiple isoforms such as CD44R, CDw44, CD44S, CD44H, and CD44E. The CD44H isoform is highly expressed in cancer tissues, indicating a potential role in tumor progression and making anti-HCAM antibody (OX49) a critical tool for cancer research. With broad reactivity and versatile applications, HCAM (OX49) monoclonal antibody serves as an invaluable resource for researchers studying cell adhesion mechanisms and their implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD44 Antibody (OX49) | sc-53068 | 200 µg/ml | $316.00 | |||
CD44 Antibody (OX49): m-IgG Fc BP-HRP Bundle | sc-538972 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD44 Antibody (OX49): m-IgG2a BP-HRP Bundle | sc-546654 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD44 Antibody (OX49) FITC | sc-53068 FITC | 200 µg/ml | $330.00 | |||
CD44 Antibody (OX49) PE | sc-53068 PE | 200 µg/ml | $343.00 |