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HCAM Antibody (F-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects HCAM in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and flow cytometry (FCM). HCAM (F-4) antibody is available in both non-conjugated and multiple conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates. HCAM, also known as CD44, is a 742 amino acid single-pass type I membrane protein that plays a crucial role in cell adhesion and migration, functioning as a receptor for hyaluronic acid (HA) and interacting with ligands like osteopontin (OPN). This interaction is vital for mediating cell-cell and cell-matrix connections, which are essential during processes such as hematopoiesis, lymphocyte activation, and tumor metastasis. HCAM′s structure includes a Link domain and is subject to alternative splicing, resulting in multiple isoforms, including CD44R, CDw44, CD44S, CD44H (hematopoietic), and CD44E (epithelial). CD44H isoform shows high expression in cancer tissues, indicating significant involvement in tumor progression and highlighting HCAM′s importance in both normal physiological processes and pathological conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD44 Antibody (F-4) | sc-9960 | 200 µg/ml | $316.00 | |||
CD44 Antibody (F-4): m-IgG Fc BP-HRP Bundle | sc-526527 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD44 Antibody (F-4): m-IgG1 BP-HRP Bundle | sc-531900 | 200 µg Ab; 20 µg BP | $354.00 | |||
CD44 Antibody (F-4) AC | sc-9960 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CD44 Antibody (F-4) HRP | sc-9960 HRP | 200 µg/ml | $316.00 | |||
CD44 Antibody (F-4) FITC | sc-9960 FITC | 200 µg/ml | $330.00 | |||
CD44 Antibody (F-4) PE | sc-9960 PE | 200 µg/ml | $343.00 | |||
CD44 Antibody (F-4) Alexa Fluor® 488 | sc-9960 AF488 | 200 µg/ml | $357.00 | |||
CD44 Antibody (F-4) Alexa Fluor® 546 | sc-9960 AF546 | 200 µg/ml | $357.00 | |||
CD44 Antibody (F-4) Alexa Fluor® 594 | sc-9960 AF594 | 200 µg/ml | $357.00 | |||
CD44 Antibody (F-4) Alexa Fluor® 647 | sc-9960 AF647 | 200 µg/ml | $357.00 | |||
CD44 Antibody (F-4) Alexa Fluor® 680 | sc-9960 AF680 | 200 µg/ml | $357.00 | |||
CD44 Antibody (F-4) Alexa Fluor® 790 | sc-9960 AF790 | 200 µg/ml | $357.00 |