HAT1 Antibody (B-10): sc-376268
- HAT1 Antibody (B-10) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 391-419 at the C-terminus of HAT1 of human origin
- recommended for detection of HAT1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for HAT1 Antibody (B-10) for WB applications. These reagents are now offered in bundles with HAT1 Antibody (B-10) (see ordering information below).
QUICK LINKS
SEE ALSO...
HAT1 Antibody (B-10) is a mouse monoclonal IgG1 antibody that detects HAT1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HAT1, or Histone Acetyltransferase 1, plays a crucial role in the acetylation of histones, specifically targeting histone H4, which is essential for the regulation of gene expression. The acetylation process mediated by HAT1 not only alters the interaction between histones and DNA, thereby facilitating a more open chromatin structure, but also serves as a signal for the recruitment of transcriptional machinery, making HAT1 vital for proper cellular function and development. Dysregulation of HAT1 has been implicated in various diseases, including cancer, where altered acetylation patterns can lead to aberrant gene expression. Anti-HAT1 antibody (B-10) is an invaluable tool for researchers studying the dynamics of histone modifications and their impact on gene regulation, providing insights into the molecular mechanisms underlying transcriptional control and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HAT1 Antibody (B-10) | sc-376268 | 200 µg/ml | $316.00 | |||
HAT1 Antibody (B-10): m-IgG Fc BP-HRP Bundle | sc-540538 | 200 µg Ab; 10 µg BP | $354.00 | |||
HAT1 Antibody (B-10): m-IgG1 BP-HRP Bundle | sc-542190 | 200 µg Ab; 20 µg BP | $354.00 | |||
HAT1 (B-10) Neutralizing Peptide | sc-376268 P | 100 µg/0.5 ml | $68.00 |