H2-I/Eκ Antibody (14-4-4S): sc-52546

H2-I/Eκ Antibody (14-4-4S) is a mouse monoclonal IgG2a light chain antibody that detects H2-I/Eκ in mouse samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). H2-I/Eκ is a crucial component of the major histocompatibility complex (MHC) class II molecules, which play a vital role in the immune response by presenting processed antigens to CD4+ T lymphocytes. Anti-H2-I/Eκ antibody (14-4-4S) recognizes a protein essential for T cell activation, which orchestrates the adaptive immune response. H2-I/Eκ is primarily located on the surface of antigen-presenting cells, including dendritic cells, macrophages, and B cells, where H2-I/Eκ facilitates the recognition of foreign peptides. The interaction between H2-I/Eκ and T cell receptors is critical for initiating immune responses, making H2-I/Eκ a key player in the body′s defense against pathogens. The structure of H2-I/Eκ, which consists of an alpha and a beta chain, allows for the binding of a diverse array of peptides, further enhancing the immune system′s ability to recognize and respond to various antigens. H2-I/Eκ monoclonal antibody (14-4-4S) serves as an invaluable tool for researchers studying immune responses and the mechanisms of antigen presentation in mouse models.

The preferred H2-I-A/I-E antibody is H2-I-A/I-E Antibody (M5/114): sc-23940.