Molecular structure of Guanabenz HCl, CAS Number: 23113-43-1
Guanabenz HCl (CAS 23113-43-1)
Alternate Names:
N-{[(2,6-dichlorophenyl)methylidene]amino}guanidine hydrochloride
CAS Number:
23113-43-1
Molecular Weight:
267.54
Molecular Formula:
C8H8Cl2N4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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SDS & Certificate of Analysis
Centrally acting α2 adrenoceptor agonist; I2 imidazoline binding site ligand; antihypertensive.
Guanabenz HCl (CAS 23113-43-1) References
- Guanabenz Reverses a Key Behavioral Change Caused by Latent Toxoplasmosis in Mice by Reducing Neuroinflammation. | Martynowicz, J., et al. 2019. mBio. 10: PMID: 31040237
- Guanabenz Attenuates Acetaminophen-Induced Liver Toxicity and Synergizes Analgesia in Mice. | Xie, W., et al. 2020. Chem Res Toxicol. 33: 162-171. PMID: 31524377
- Guanabenz modulates microglia and macrophages during demyelination. | Thompson, KK. and Tsirka, SE. 2020. Sci Rep. 10: 19333. PMID: 33168944
- Guanabenz Sensitizes Glioblastoma Cells to Sunitinib by Inhibiting GADD34-Mediated Autophagic Signaling. | Ho, KH., et al. 2021. Neurotherapeutics. 18: 1371-1392. PMID: 33410111
- Guanabenz and Clonidine, α2-Adrenergic Receptor Agonists, Inhibit Choroidal Neovascularization. | Tanaka, M., et al. 2021. Curr Neurovasc Res. 18: 85-92. PMID: 34011258
- Guanabenz inhibits alveolar bone resorption in a rat model of periodontitis. | Muramatsu, R., et al. 2021. J Pharmacol Sci. 147: 294-304. PMID: 34507638
- Guanabenz mitigates the neuropathological alterations and cell death in Alzheimer's disease. | Singh, A., et al. 2022. Cell Tissue Res. 388: 239-258. PMID: 35195784
- Guanabenz-an old drug with a potential to decrease obesity. | Kotańska, M., et al. 2022. Naunyn Schmiedebergs Arch Pharmacol. 395: 963-974. PMID: 35511242
- Guanabenz ameliorates disease in vanishing white matter mice in contrast to sephin1. | Witkamp, D., et al. 2022. Ann Clin Transl Neurol. 9: 1147-1162. PMID: 35778832
- Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension. | Holmes, B., et al. 1983. Drugs. 26: 212-29. PMID: 6352237
Inhibitor of:
(eukaryotic translation initiation factor) eIF, ATF-6β, Bet1, CHP2, Dexras2, DnaJC5γ, eIF1AY, eIF2α, eIF2Bα, eIF2Bδ, eIF3M, eIF4B, eIF5A1, GADD 34, Hsp104, HUGT2, KIAA0141, KIAA0406, Membralin, P-Selectin, PERK, PPP1R15B, Ramp4-2, Sec13, Sel-1L2, SIL1, Synoviolin, VAP-A, and XTP3-B.Activator of:
Atlastin-3, CSP, Derlin-2, DnaJC3, eIF2A, eIF2Bγ, HYPK, PDILT, prefoldin 3, SCRG1, Sec63, and TSR3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Guanabenz HCl, 100 mg | sc-507500 | 100 mg | $241.00 |