GSTT Antibody (D-1): sc-393035
- GSTT Antibody (D-1) is a mouse monoclonal IgG1 κ GSTT antibody provided at 200 µg/ml
- raised against amino acids 1-240 representing full length GSTT1 of human origin
- GSTT Antibody (D-1) is recommended for detection of GSTT1 and GSTT3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-GSTT Antibody (D-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GSTT Antibody (D-1). This work is in progress.
QUICK LINKS
GSTT Antibody (D-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects GSTT protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-GSTT antibody (D-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GSTT protein, a member of the glutathione S-transferase superfamily, plays a crucial role in detoxifying harmful compounds by catalyzing the conjugation of reduced glutathione to a wide range of endogenous and exogenous hydrophobic electrophiles, thereby protecting cells from oxidative stress and damage. GSTT protein functions as a homodimer in erythrocytes, contributing to cellular defense mechanisms. GSTT1 exhibits glutathione peroxidase activity, which is vital for neutralizing reactive oxygen species, further underscoring its significance in maintaining cellular health. GSTT (D-1) antibody′s versatility in various applications makes this reagent an essential tool for researchers studying GSTT in different biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GSTT Antibody (D-1) References:
- Characterization of the glutathione S-transferase GSTT1 deletion: discrimination of all genotypes by polymerase chain reaction indicates a trimodular genotype-phenotype correlation. | Sprenger, R., et al. 2000. Pharmacogenetics. 10: 557-65. PMID: 10975610
- Theta, a new class of glutathione transferases purified from rat and man. | Meyer, DJ., et al. 1991. Biochem J. 274 (Pt 2): 409-14. PMID: 1848757
- Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. | Pemble, S., et al. 1994. Biochem J. 300 (Pt 1): 271-6. PMID: 8198545
- The distribution of theta-class glutathione S-transferases in the liver and lung of mouse, rat and human. | Mainwaring, GW., et al. 1996. Biochem J. 318 (Pt 1): 297-303. PMID: 8761485
- Kinetic characterization of recombinant human glutathione transferase T1-1, a polymorphic detoxication enzyme. | Jemth, P. and Mannervik, B. 1997. Arch Biochem Biophys. 348: 247-54. PMID: 9434735
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GSTT Antibody (D-1) | sc-393035 | 200 µg/ml | $322.00 | |||
GSTT Antibody (D-1) AC | sc-393035 AC | 500 µg/ml, 25% agarose | $424.00 | |||
GSTT Antibody (D-1) HRP | sc-393035 HRP | 200 µg/ml | $322.00 | |||
GSTT Antibody (D-1) FITC | sc-393035 FITC | 200 µg/ml | $336.00 | |||
GSTT Antibody (D-1) PE | sc-393035 PE | 200 µg/ml | $349.00 | |||
GSTT Antibody (D-1) Alexa Fluor® 488 | sc-393035 AF488 | 200 µg/ml | $364.00 | |||
GSTT Antibody (D-1) Alexa Fluor® 546 | sc-393035 AF546 | 200 µg/ml | $364.00 | |||
GSTT Antibody (D-1) Alexa Fluor® 594 | sc-393035 AF594 | 200 µg/ml | $364.00 | |||
GSTT Antibody (D-1) Alexa Fluor® 647 | sc-393035 AF647 | 200 µg/ml | $364.00 | |||
GSTT Antibody (D-1) Alexa Fluor® 680 | sc-393035 AF680 | 200 µg/ml | $364.00 | |||
GSTT Antibody (D-1) Alexa Fluor® 790 | sc-393035 AF790 | 200 µg/ml | $364.00 |