Anti-golgin 84 Antibody (D-5) is a mouse monoclonal IgG1 κ golgin 84 antibody, cited in 1 publications, provided at 200 µg/ml
raised against amino acids 343-625 mapping within an internal region of golgin 84 of human origin
Anti-golgin 84 Antibody (D-5) is recommended for detection of golgin 84 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
Anti-golgin 84 Antibody (D-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of golgin 84 (D-5): sc-365337.
At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for golgin 84 Antibody (D-5). This work is in progress.
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golgin 84 Antibody (D-5) is a high quality monoclonal golgin 84 antibody (also designated golgin 84 antibody) suitable for the detection of the golgin 84 protein of mouse, rat and human origin. golgin 84 Antibody (D-5) is available as both the non-conjugated anti-golgin 84 antibody form, as well as multiple conjugated forms of anti-golgin 84 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Golgin 84, also known as GOLGA5 (Golgi autoantigen, subfamily A, member 5), RFG5 (RET-fused gene 5 protein) or GOLIM5, is a ubiquitously expressed single-pass type II coiled-coil membrane protein. Localizing to the Golgi apparatus and predominantly found on membranes at the cis side of the Golgi stack, golgin 84 participates in the maintenance of Golgi structure and the formation of Golgi stacks and ribbons. The depletion of golgin 84 leads to fragmentation of the Golgi ribbon and reduced efficiency in protein transport. In addition, golgin 84 binds to active Rab 1 and associates with CASP (an isoform of CDP) in a golgin-tethering complex that is believed to play a role in intra-Golgi retrograde transport. During mitosis, golgin 84 is highly phosphorylated. Chromosomal translocations involving the gene encoding golgin 84 have been associated with cancer tissues. The chimeric proteins produced by this translocation are known as Ret-II and PTC5.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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