golgin 160 Antibody (C-8): sc-374596
- golgin 160 Antibody (C-8) is a mouse monoclonal IgG1 κ golgin 160 antibody provided at 200 µg/ml
- raised against amino acids 371-670 mapping within an internal region of golgin 160 of human origin
- golgin 160 Antibody (C-8) is recommended for detection of golgin 160 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-golgin 160 Antibody (C-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for golgin 160 Antibody (C-8) for WB applications. These reagents are now offered in bundles with golgin 160 Antibody (C-8) (see ordering information below).
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golgin 160 Antibody (C-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects golgin 160 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-golgin 160 antibody (C-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. golgin 160, also known as GOLGA3 (Golgin subfamily A member 3), MEA-2, or GCP170, is a 1,498 amino acid protein characterized by coiled-coil domains and is primarily localized to the cytoplasm and Golgi apparatus. golgin 160 plays a crucial role in maintaining the structure of the Golgi apparatus, which is essential for proper transport of lipids and proteins within the secretory pathway. golgin 160 functions as a homodimer and interacts with GOLGA7, contributing to Golgi organization and potentially influencing nuclear transport and Golgi localization. golgin 160 expression is observed in various tissues, including heart, liver, testis, kidney, lung, and salivary gland, and multiple isoforms arise from alternative splicing events, highlighting functional diversity and importance in cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
golgin 160 Antibody (C-8) References:
- The NH2-terminal domain of Golgin-160 contains both Golgi and nuclear targeting information. | Hicks, SW. and Machamer, CE. 2002. J Biol Chem. 277: 35833-9. PMID: 12130652
- Identification and characterization of GCP16, a novel acylated Golgi protein that interacts with GCP170. | Ohta, E., et al. 2003. J Biol Chem. 278: 51957-67. PMID: 14522980
- Phosphorylation of golgin-160 by mixed lineage kinase 3. | Cha, H., et al. 2004. J Cell Sci. 117: 751-60. PMID: 14734651
- Caspase-resistant Golgin-160 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors. | Maag, RS., et al. 2005. Mol Biol Cell. 16: 3019-27. PMID: 15829563
- Isoform-specific interaction of golgin-160 with the Golgi-associated protein PIST. | Hicks, SW. and Machamer, CE. 2005. J Biol Chem. 280: 28944-51. PMID: 15951434
- Involvement of Golgin-160 in cell surface transport of renal ROMK channel: co-expression of Golgin-160 increases ROMK currents. | Bundis, F., et al. 2006. Cell Physiol Biochem. 17: 1-12. PMID: 16543716
- GCP60 preferentially interacts with a caspase-generated golgin-160 fragment. | Sbodio, JI., et al. 2006. J Biol Chem. 281: 27924-31. PMID: 16870622
- Golgin-160 is required for the Golgi membrane sorting of the insulin-responsive glucose transporter GLUT4 in adipocytes. | Williams, D., et al. 2006. Mol Biol Cell. 17: 5346-55. PMID: 17050738
- Golgin-160 promotes cell surface expression of the beta-1 adrenergic receptor. | Hicks, SW., et al. 2006. Traffic. 7: 1666-77. PMID: 17118120
- Identification of a redox-sensitive cysteine in GCP60 that regulates its interaction with golgin-160. | Sbodio, JI. and Machamer, CE. 2007. J Biol Chem. 282: 29874-81. PMID: 17711851
- Golgin-160 and GMAP210 play an important role in U251 cells migration and invasion initiated by GDNF. | Tang, CX., et al. 2019. PLoS One. 14: e0211501. PMID: 30695072
- Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex. | Fritzler, MJ., et al. 1993. J Exp Med. 178: 49-62. PMID: 8315394
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
golgin 160 Antibody (C-8) | sc-374596 | 200 µg/ml | $322.00 | |||
golgin 160 Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-527486 | 200 µg Ab; 10 µg BP | $361.00 | |||
golgin 160 Antibody (C-8): m-IgG1 BP-HRP Bundle | sc-532859 | 200 µg Ab; 20 µg BP | $361.00 | |||
golgin 160 Antibody (C-8) AC | sc-374596 AC | 500 µg/ml, 25% agarose | $424.00 | |||
golgin 160 Antibody (C-8) HRP | sc-374596 HRP | 200 µg/ml | $322.00 | |||
golgin 160 Antibody (C-8) FITC | sc-374596 FITC | 200 µg/ml | $336.00 | |||
golgin 160 Antibody (C-8) PE | sc-374596 PE | 200 µg/ml | $349.00 | |||
golgin 160 Antibody (C-8) Alexa Fluor® 488 | sc-374596 AF488 | 200 µg/ml | $364.00 | |||
golgin 160 Antibody (C-8) Alexa Fluor® 546 | sc-374596 AF546 | 200 µg/ml | $364.00 | |||
golgin 160 Antibody (C-8) Alexa Fluor® 594 | sc-374596 AF594 | 200 µg/ml | $364.00 | |||
golgin 160 Antibody (C-8) Alexa Fluor® 647 | sc-374596 AF647 | 200 µg/ml | $364.00 | |||
golgin 160 Antibody (C-8) Alexa Fluor® 680 | sc-374596 AF680 | 200 µg/ml | $364.00 | |||
golgin 160 Antibody (C-8) Alexa Fluor® 790 | sc-374596 AF790 | 200 µg/ml | $364.00 |