Gl Syn Antibody (E-2): sc-398017
- Gl Syn Antibody (E-2) is a mouse monoclonal IgG3 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 281-312 near the C-terminus of Gl Syn of human origin
- recommended for detection of Gl Syn of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG3 BP-HRP is the preferred secondary detection reagent for Gl Syn Antibody (E-2) for WB and IHC(P) applications. This reagent is now offered in a bundle with Gl Syn Antibody (E-2) (see ordering information below).
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Gl Syn Antibody (E-2) is a mouse monoclonal IgG3 antibody that detects glutamine synthetase (Gl Syn) in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Glutamine synthetase plays a crucial role in the brain by catalyzing the conversion of glutamic acid to glutamine, a process vital for maintaining neurotransmitter balance and preventing excitotoxicity, which can lead to neuronal damage. Gl Syn (E-2) monoclonal antibody recognizes glutamine synthetase predominantly in astrocytes, where expression is significantly induced upon contact with neurons, highlighting its importance in neuroprotection. Additionally, glutamine synthetase is present in the liver, where glutamine synthetase contributes to nitrogen homeostasis, and glutamine synthetase overexpression has been associated with primary liver cancers, suggesting a potential role in hepatocyte transformation. Anti-Gl Syn antibody (E-2) serves as an essential tool for researchers studying glutamine synthetase dynamics in various physiological and pathological contexts, providing insights into function and interactions within the cellular environment.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gl Syn Antibody (E-2) | sc-398017 | 200 µg/ml | $322.00 | |||
Gl Syn Antibody (E-2): m-IgG3 BP-HRP Bundle | sc-550502 | 200 µg Ab; 40 µg BP | $361.00 | |||
Gl Syn (E-2) Neutralizing Peptide | sc-398017 P | 100 µg/0.5 ml | $69.00 |