GIPC2 Antibody (G-7): sc-515441
- GIPC2 Antibody (G-7) is a mouse monoclonal IgG1 κ GIPC2 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 169-187 within an internal region of GIPC2 of human origin
- GIPC2 Antibody (G-7) is recommended for detection of GIPC2 of human origin by WB, IP, IF and ELISA
- Anti-GIPC2 Antibody (G-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for GIPC2 Antibody (G-7) for WB applications. These reagents are now offered in bundles with GIPC2 Antibody (G-7) (see ordering information below).
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GIPC2 Antibody (G-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects GIPC2 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GIPC2 (G-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GIPC2, also known as SEMCAP2, is a 315 amino acid protein that plays a crucial role in cellular signaling and organization due to its PDZ domain, which is a multifunctional protein-protein interaction motif. This domain is essential for the clustering of signaling molecules and the formation of protein networks, making GIPC2 vital for processes such as cell adhesion and growth factor signaling. GIPC2 is predominantly expressed in the kidney and colon, with lower expression levels in the adult liver, and GIPC2 interacts with proteins like SEMA5A, suggesting involvement in modulating cellular responses that can influence tumorigenesis. The gene encoding GIPC2 is located on human chromosome 1, which encompasses a large portion of the human genome, containing over 3,000 genes and spanning 260 million base pairs. This extensive genetic landscape highlights GIPC2′s importance in various biological processes and potential implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GIPC2 Antibody (G-7) References:
- Molecular cloning and characterization of human GIPC2, a novel gene homologous to human GIPC1 and Xenopus Kermit. | Kirikoshi, H. and Katoh, M. 2002. Int J Oncol. 20: 571-6. PMID: 11836570
- Expression of human GIPC1 in normal tissues, cancer cell lines, and primary tumors. | Kirikoshi, H. and Katoh, M. 2002. Int J Mol Med. 9: 509-13. PMID: 11956658
- GIPC gene family (Review). | Katoh, M. 2002. Int J Mol Med. 9: 585-9. PMID: 12011974
- Up-regulation of GIPC2 in human gastric cancer. | Kirikoshi, H. and Katoh, M. 2002. Int J Oncol. 20: 1183-7. PMID: 12011997
- Expression of WNT7A in human normal tissues and cancer, and regulation of WNT7A and WNT7B in human cancer. | Kirikoshi, H. and Katoh, M. 2002. Int J Oncol. 21: 895-900. PMID: 12239632
- Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis. | Katoh, M. 2007. Stem Cell Rev. 3: 30-8. PMID: 17873379
- Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia. | Kuang, SQ., et al. 2008. Leukemia. 22: 1529-38. PMID: 18528427
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GIPC2 Antibody (G-7) | sc-515441 | 200 µg/ml | $316.00 | |||
GIPC2 Antibody (G-7): m-IgG Fc BP-HRP Bundle | sc-528036 | 200 µg Ab; 10 µg BP | $354.00 | |||
GIPC2 Antibody (G-7): m-IgG1 BP-HRP Bundle | sc-533409 | 200 µg Ab; 20 µg BP | $354.00 | |||
GIPC2 Antibody (G-7) AC | sc-515441 AC | 500 µg/ml, 25% agarose | $416.00 | |||
GIPC2 Antibody (G-7) HRP | sc-515441 HRP | 200 µg/ml | $316.00 | |||
GIPC2 Antibody (G-7) FITC | sc-515441 FITC | 200 µg/ml | $330.00 | |||
GIPC2 Antibody (G-7) PE | sc-515441 PE | 200 µg/ml | $343.00 | |||
GIPC2 Antibody (G-7) Alexa Fluor® 488 | sc-515441 AF488 | 200 µg/ml | $357.00 | |||
GIPC2 Antibody (G-7) Alexa Fluor® 546 | sc-515441 AF546 | 200 µg/ml | $357.00 | |||
GIPC2 Antibody (G-7) Alexa Fluor® 594 | sc-515441 AF594 | 200 µg/ml | $357.00 | |||
GIPC2 Antibody (G-7) Alexa Fluor® 647 | sc-515441 AF647 | 200 µg/ml | $357.00 | |||
GIPC2 Antibody (G-7) Alexa Fluor® 680 | sc-515441 AF680 | 200 µg/ml | $357.00 | |||
GIPC2 Antibody (G-7) Alexa Fluor® 790 | sc-515441 AF790 | 200 µg/ml | $357.00 | |||
GIPC2 (G-7) Neutralizing Peptide | sc-515441 P | 100 µg/0.5 ml | $68.00 |