GH Antibody (NYRhGH): sc-73289
- GH Antibody (NYRhGH) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against recombinant GH of human origin
- recommended for detection of GH of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GH Antibody (NYRhGH). This work is in progress.
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GH Antibody (NYRhGH) is a mouse monoclonal IgG1 antibody that detects growth hormone (GH) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). GH, also known as somatotropin, is a pivotal hormone produced by the acidophilic cells of the anterior pituitary gland, consisting of 191 amino acid residues and characterized by the presence of two disulfide bridges that contribute to structural stability. Anti-GH antibody (NYRhGH) enables researchers to study GH′s role in stimulating growth, metabolism, and differentiation across various mammalian cell types, achieved through interaction with growth hormone receptor (GHR) on target cells. This binding initiates a phosphorylation cascade that activates multiple signaling pathways essential for cellular function and development. GH is secreted in a pulsatile manner, regulated by hypothalamic hormones GH-releasing hormone (GHRH) and somatostatin (SRIF), which finely tune synthesis and release. Additionally, GH secretion is subject to feedback inhibition by insulin-like growth factor I, ensuring homeostasis within the endocrine system. GH monoclonal antibody (NYRhGH) serves as an invaluable tool for researchers studying the intricate mechanisms of growth regulation and physiological effects of GH in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GH Antibody (NYRhGH) | sc-73289 | 100 µg/ml | $316.00 |