GH Antibody (GhB9): sc-51910
- GH Antibody (GhB9) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against purified recombinant human growth hormone
- recommended for detection of GH of human origin by WBIPELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GH Antibody (GhB9). This work is in progress.
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GH Antibody (GhB9) is a mouse monoclonal IgG1 antibody that detects growth hormone (GH) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). GH plays a vital role in regulating growth, metabolism, and differentiation across various mammalian cell types by influencing the synthesis of multiple mRNA species. Anti-GH antibody (GhB9) binds specifically to membrane-bound growth hormone receptor (GHR), initiating a phosphorylation cascade that activates numerous signaling pathways essential for cellular function and development. GH is secreted in a pulsatile manner, tightly regulated by the hypothalamic hormones GH-releasing hormone (GHRH) and somatostatin (SRIF), which together orchestrate GH synthesis and release from somatotropic cells in the anterior pituitary gland. GH output is subject to feedback regulation by GH levels and insulin-like growth factor I, ensuring a balanced physiological response. The structure of human growth hormone, consisting of 191 amino acid residues and featuring two disulfide bridges, is crucial for stability and biological activity, making GH monoclonal antibody (GhB9) an essential tool for researchers studying growth regulation and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GH Antibody (GhB9) | sc-51910 | 100 µg/ml | $322.00 |