GGPL-I Antibody (LI-77): sc-13570

GGPL-I Antibody (LI-77) is a mouse monoclonal IgM antibody that detects the GGPL-I protein of Mycoplasma fermentans origin by enzyme-linked immunosorbent assay (ELISA). Anti-GGPL-I antibody (LI-77) is available as the non-conjugated format, providing researchers with a reliable tool for studying this important protein. GGPL-I plays a crucial role in the unique choline metabolic pathway of Mycoplasma fermentans, which is responsible for generating phosphocholine-containing glycoglycerolipids, including GGPL-I and GGPL-III. These glycoglycerolipids are significant because they are involved in the organism′s membrane structure and function, influencing its interaction with host cells and immune evasion strategies. Notably, the presence of antibodies against GGPL-III is markedly higher in the sera of individuals infected with HIV-1 compared to healthy donors, suggesting a potential link between Mycoplasma fermentans and the pathogenesis of acquired immunodeficiency syndrome (AIDS). Understanding the role of GGPL-I and its associated glycoglycerolipids can provide insights into the mechanisms of Mycoplasma-related diseases and their impact on human health.

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GGPL-I Antibody (LI-77) References:

1. Monoclonal antibody against Mycoplasma fermentans-specific aminoglycoglycerolipid.  |  Matsuda, K., et al. 2000. Microbiol Immunol. 44: 695-702. PMID: 11021400
2. Identification of phosphocholine-containing glycoglycerolipids purified from Mycoplasma fermentans-infected human helper T-cell culture as components of M. fermentans.  |  Matsuda, K., et al. 1995. Microbiol Immunol. 39: 307-13. PMID: 7565170
3. Phosphocholine-containing glycoglycerolipids (GGPL-I and GGPL-III) are species-specific major immunodeterminants of Mycoplasma fermentans.  |  Matsuda, K., et al. 1997. Biochem Biophys Res Commun. 233: 644-9. PMID: 9168906
4. Structure of a novel phosphocholine-containing aminoglycoglycerolipid of Mycoplasma fermentans.  |  Matsuda, K., et al. 1997. Biochim Biophys Acta. 1349: 1-12. PMID: 9421191
5. Detection of serum antibodies against phosphocholine-containing aminoglycoglycerolipid specific to Mycoplasma fermentans in HIV-1 infected individuals.  |  Li, JL., et al. 1997. J Immunol Methods. 208: 103-13. PMID: 9433466

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-GGPL-I Antibody (LI-77) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

GGPL-I Antibody (LI-77) Specifications

Alternate Product Name: GGPL-I

Product Clone Name: LI-77

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM

Amino Acids:

Epitope Target: GGPL-I

Epitope Species: Mycoplasma fermentans

Product Reactivity/Detection: GGPL-I

Species Reactivity/Detection: Mycoplasma fermentans

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 200 µg IgM in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for GGPL-I Antibody (LI-77): N/A