GDF-7 Antibody (AA-9): sc-81951
- GDF-7 Antibody (AA-9) is a mouse monoclonal IgG2b κ provided at 50 µg/0.5 ml
- raised against recombinant GDF-7 of human origin
- recommended for detection of GDF-7 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GDF-7 Antibody (AA-9). This work is in progress.
GDF-7 Antibody (AA-9) is a mouse monoclonal IgG2b antibody that detects GDF-7 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). GDF-7, a member of the growth/differentiation factor family within the transforming growth factor-beta (TGF-β) superfamily, plays a crucial role in the development and maintenance of various tissues, particularly in the nervous system and musculoskeletal system. Anti-GDF-7 antibody (AA-9) recognizes a protein primarily expressed in the central nervous system that′s essential for neural progenitor cell differentiation, vital for proper brain development and function. GDF-7 has been implicated in bone and cartilage formation regulation, making GDF-7 significant in skeletal health and disease. GDF-7 monoclonal antibody (AA-9) targets a protein that interacts with other members of the TGF-β superfamily, influencing signaling pathways governing cellular processes like proliferation, differentiation, and apoptosis. GDF-7′s ability to modulate these pathways underscores its importance in both developmental biology and potential therapeutic applications, particularly in regenerative medicine and tissue engineering.
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GDF-7 Antibody (AA-9) References:
- Achilles tendon characterization in GDF-7 deficient mice. | Mikic, B., et al. 2006. J Orthop Res. 24: 831-41. PMID: 16514625
- Geometric and material contributions to whole bone structural behavior in GDF-7-deficient mice. | Maloul, A., et al. 2006. Connect Tissue Res. 47: 157-62. PMID: 16753809
- Effect of GDF-7 deficiency on tail tendon phenotype in mice. | Mikic, B., et al. 2008. J Orthop Res. 26: 834-9. PMID: 18240333
- Accelerated hypertrophic chondrocyte kinetics in GDF-7 deficient murine tibial growth plates. | Mikic, B., et al. 2008. J Orthop Res. 26: 986-90. PMID: 18302280
- Dual-mode blue emission, enhanced up-conversion luminescence and paramagnetic properties of ytterbium and thulium-doped Ba2GdF7 multifunctional nanophosphors. | Li, H., et al. 2017. J Colloid Interface Sci. 501: 215-221. PMID: 28456105
- Tenogenic Differentiation of Human Embryonic Stem Cells. | Dale, TP., et al. 2018. Tissue Eng Part A. 24: 361-368. PMID: 28548630
- Renal-Clearable Peptide-Functionalized Ba2GdF7 Nanoparticles for Positive Tumor-Targeting Dual-Mode Bioimaging. | Feng, Y., et al. 2018. ACS Appl Mater Interfaces. 10: 25511-25518. PMID: 29989405
- Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells. | Ding, M., et al. 2021. Sci Rep. 11: 16767. PMID: 34408239
- Growth Differentiation Factor 7 promotes multiple-lineage differentiation in tenogenic cultures of mesenchymal stem cells. | Kumlin, M., et al. 2022. Injury. 53: 4165-4168. PMID: 36261312
- Growth and differentiation factor-7 immobilized, mechanically strong quadrol-hexamethylene diisocyanate-methacrylic anhydride polyurethane polymer for tendon repair and regeneration. | Wang, D., et al. 2022. Acta Biomater. 154: 108-122. PMID: 36272687
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GDF-7 Antibody (AA-9) | sc-81951 | 50 µg/0.5 ml | $316.00 |