Gas7 Antibody (D-2): sc-365372

Gas7 Antibody (D-2) is a mouse monoclonal IgG2a antibody that detects Gas7 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Gas7 is a critical growth arrest-specific protein that plays a significant role in neurite differentiation, particularly in cultured mouse cerebellar neurons and PC-12 cells, highlighting Gas7′s potential as a therapeutic target for promoting neuronal connection re-establishment in injured or diseased brains. Gas7 is expressed in three isoforms—Gas7a, Gas7b, and Gas7c—each exhibiting differential expression across various brain subregions, which is essential for understanding specific functions in neurodevelopment and repair mechanisms. Additionally, the gene encoding human Gas7 is located on chromosome 17p13.1, where Gas7 can translocate with the MLL gene, leading to the formation of MLL-GAS7 fusion products that may have implications in certain leukemias. Anti-Gas7 antibody (D-2) provides a valuable tool for researchers investigating the intricate roles of Gas7 in neuronal health and disease, enabling deeper insights into molecular interactions and potential therapeutic applications.

The preferred Gas7 antibody is Gas7 Antibody (H-9): sc-365385.