γ-taxilin Antibody (F-4): sc-393721
- γ-taxilin Antibody (F-4) is a mouse monoclonal IgM κ γ-taxilin antibody provided at 200 µg/ml
- raised against amino acids 49-136 mapping near the N-terminus of γ-taxilin of human origin
- recommended for detection of γ-taxilin of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for γ-taxilin Antibody (F-4). This work is in progress.
γ-taxilin Antibody (F-4) is a mouse monoclonal IgM kappa antibody that detects gamma-taxilin protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). γ-taxilin (F-4) antibody is available as the non-conjugated form. Gamma-taxilin, also known as lipopolysaccharide-specific response protein 5, plays a crucial role in cellular processes, particularly in heart and skeletal muscle where gamma-taxilin is highly expressed. Gamma-taxilin is involved in regulating the nascent polypeptide-associated complex (NAC), which is essential for proper folding and processing of newly synthesized proteins. Gamma-taxilin′s interaction with the alpha subunit of NAC not only influences nuclear distribution but also suggests a broader role in transcriptional regulation, highlighting gamma-taxilin′s importance in maintaining cellular homeostasis and responding to stress signals. Gamma-taxilin is expressed in various tissues, including brain, placenta, lung, liver, kidney, and pancreas, indicating gamma-taxilin′s potential involvement in diverse physiological functions across different organ systems.
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γ-taxilin Antibody (F-4) References:
- Taxilin; a novel syntaxin-binding protein that is involved in Ca2+-dependent exocytosis in neuroendocrine cells. | Nogami, S., et al. 2003. Genes Cells. 8: 17-28. PMID: 12558796
- Interaction of taxilin with syntaxin which does not form the SNARE complex. | Nogami, S., et al. 2003. Biochem Biophys Res Commun. 311: 797-802. PMID: 14623251
- Identification and characterization of taxilin isoforms. | Nogami, S., et al. 2004. Biochem Biophys Res Commun. 319: 936-43. PMID: 15184072
- Interaction of the taxilin family with the nascent polypeptide-associated complex that is involved in the transcriptional and translational processes. | Yoshida, K., et al. 2005. Genes Cells. 10: 465-76. PMID: 15836775
- Estrogen modulation of hypothalamic neurons: activation of multiple signaling pathways and gene expression changes. | Malyala, A., et al. 2005. Steroids. 70: 397-406. PMID: 15862823
- Inhibition of ATF4 transcriptional activity by FIAT/gamma-taxilin modulates bone mass accrual. | Yu, VW., et al. 2006. Ann N Y Acad Sci. 1068: 131-42. PMID: 16831913
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
γ-taxilin Antibody (F-4) | sc-393721 | 200 µg/ml | $322.00 |