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γ-Oryzanol (CAS 11042-64-1)

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Alternate Names:
Gammariza; Gamma-orizanol
Application:
γ-Oryzanol is a potent membrane antioxidant
CAS Number:
11042-64-1
Purity:
≥99%
Molecular Weight:
602.89
Molecular Formula:
C40H58O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Gamma-Oryzanol, also known as g-Oryzanol, is a naturally occurring compound abundant in various food sources, particularly rice bran oil. It comprises a blend of ferulic acid esters derived from triterpene alcohols and sterols, such as cycloartenol, 24-methylene cycloartanol, and campesterol. This compound exhibits potential antioxidant and anti-inflammatory properties by effectively scavenging free radicals, impeding the generation of inflammatory mediators, and regulating the activity of enzymes implicated in oxidative stress and inflammation.


γ-Oryzanol (CAS 11042-64-1) References

  1. Antiadipogenic Activity of γ-Oryzanol and Its Stability in Pigmented Rice.  |  Minatel, IO., et al. 2016. J Med Food. 19: 710-5. PMID: 27309274
  2. Antioxidant Activity of γ-Oryzanol: A Complex Network of Interactions.  |  Minatel, IO., et al. 2016. Int J Mol Sci. 17: PMID: 27517904
  3. Brown rice-specific γ-oryzanol as a promising prophylactic avenue to protect against diabetes mellitus and obesity in humans.  |  Masuzaki, H., et al. 2019. J Diabetes Investig. 10: 18-25. PMID: 29978570
  4. γ-Oryzanol Improves Cognitive Function and Modulates Hippocampal Proteome in Mice.  |  Rungratanawanich, W., et al. 2019. Nutrients. 11: PMID: 30935111
  5. Absorption and Metabolism of γ-Oryzanol, a Characteristic Functional Ingredient in Rice Bran.  |  Sawada, K., et al. 2019. J Nutr Sci Vitaminol (Tokyo). 65: S180-S184. PMID: 31619625
  6. Rice Components with Immunomodulatory Function.  |  Toda, M. 2019. J Nutr Sci Vitaminol (Tokyo). 65: S9-S12. PMID: 31619655
  7. Extraction of γ-oryzanol from rice bran using diverse edible oils: enhancement in oxidative stability of oils.  |  Yi, B. and Kim, MJ. 2020. Food Sci Biotechnol. 29: 393-399. PMID: 32257523
  8. Biological and Pharmacological Effects of Gamma-oryzanol: An Updated Review of the Molecular Mechanisms.  |  Ramazani, E., et al. 2021. Curr Pharm Des. 27: 2299-2316. PMID: 33138751
  9. Interactions between α-tocopherol and γ-oryzanol in oil-in-water emulsions.  |  Liu, R., et al. 2021. Food Chem. 356: 129648. PMID: 33819788
  10. γ-Oryzanol Improves Exercise Endurance and Muscle Strength by Upregulating PPARδ and ERRγ Activity in Aged Mice.  |  Ahn, J., et al. 2021. Mol Nutr Food Res. 65: e2000652. PMID: 33932312
  11. Effect of triacylglycerol structure on the antioxidant activity of γ-oryzanol.  |  Toorani, MR. and Golmakani, MT. 2022. Food Chem. 370: 130974. PMID: 34500298
  12. Neuronal Induction of Bone-Fat Imbalance through Osteocyte Neuropeptide Y.  |  Zhang, Y., et al. 2021. Adv Sci (Weinh). 8: e2100808. PMID: 34719888
  13. Phytosterols and γ-Oryzanol as Cholesterol Solid Phase Modifiers during Digestion.  |  Esperança, ES., et al. 2022. Foods. 11: PMID: 36429220

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

γ-Oryzanol, 25 g

sc-295006
25 g
$60.00

γ-Oryzanol, 250 g

sc-295006A
250 g
$315.00

Hello, Why is this material considered as dangerous goods?

Asked by: Syaga
Thank you for your question. Here is the safety data sheet :https://datasheets.scbt.com/sds/aghs/en/sc-295006.pdf
Answered by: BlakeJ
Date published: 2022-11-22

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. The compound, sc-295006, is provided as a white powder. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-01-12
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Rated 5 out of 5 by from AraujoAraujo, SM. et al. (PubMed 26366809) demonstrated that -Oryzanol (Gammariza; Gamma-orizanol), a potent membrane antioxidant, is effective in reducing the rotenone induced toxicity in D. melanogaster, which showed neuroprotective action. -SCBT Publication Review
Date published: 2015-02-17
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γ-Oryzanol is rated 5.0 out of 5 by 1.
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