G_{α q/11} Antibody (F-5): sc-515689

Gα q/11 Antibody (F-5) is a mouse monoclonal IgG2b antibody that detects Gα q/11 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Gα q/11 is a crucial member of the heterotrimeric G protein family, which plays a vital role in transmitting signals from various cell surface receptors to intracellular effectors, thereby influencing numerous physiological processes. Specifically, Gα q/11 is involved in the activation of phospholipase C, leading to the production of inositol trisphosphate and diacylglycerol, which are essential for calcium signaling and the activation of protein kinase C. This signaling pathway is particularly important in the context of cardiovascular function, neuronal signaling, and immune responses, as Gα q/11 regulates various cellular activities such as muscle contraction, neurotransmitter release, and cell proliferation. Gα q/11 is predominantly located in the plasma membrane, where Gα q/11 interacts with a variety of receptors, including those for hormones and neurotransmitters, making Gα q/11 a key player in mediating extracellular signals. anti-Gα q/11 antibody (F-5) is an invaluable tool for researchers aiming to explore the intricate signaling mechanisms involving G proteins and their implications in health and disease.

The preferred G_{α q} antibody is G_{α q} Antibody (10): sc-136181.