galectin-3 Antibody (M3/38): sc-23938
- galectin-3 Antibody (M3/38) is a rat monoclonal IgG2a, cited in 59 publications, provided at 200 µg/ml
- raised against Galectin-3 of mouse origin
- Anti-galectin-3 Antibody (M3/38) is recommended for detection of Galectin-3 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- Anti-galectin-3 Antibody (M3/38) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for galectin-3 Antibody (M3/38). This work is in progress.
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SEE ALSO...
Galectin-3 Antibody (M3/38) is a rat monoclonal IgG2a antibody engineered to target galectin-3, also known by its alternate names Mac-2, hMac-2 (human Mac-2), GALBP (galactose-binding protein), CBP35 (carbohydrate-binding protein 35), and LGALS3 (lectin, galactoside-binding, soluble, 3). Anti-galectin-3 antibody (M3/38) is raised against galectin-3 of mouse origin and is recommended for the detection of galectin-3 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Galectin-3 is a pivotal member of the galectin family of soluble β-galactoside-binding lectins that play essential roles in modulating cell-to-cell adhesion and interactions between cells and the extracellular matrix (ECM), which are critical for processes such as tissue development, immune response, and cellular communication. Located both intracellularly in the cytoplasm and nucleus, and extracellularly in the ECM, galectin-3′s cellular localization is crucial for its diverse functions. Intracellularly, galectin-3 is involved in signaling pathways, pre-mRNA splicing, and apoptosis, while extracellularly, galectin-3 facilitates cell adhesion, migration, and interactions with the ECM. These functions make galectin-3 integral to maintaining cellular homeostasis and responding to cellular stress. Importantly, galectin-3 is implicated in tumor progression and metastasis by influencing cancer cell proliferation, apoptosis resistance, and angiogenesis, thereby making galectin-3 a significant target in cancer research. Galectin-3 (M3/38) antibody is available in both non-conjugated form and multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, providing versatile options for diverse experimental applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
galectin-3 Antibody (M3/38) | sc-23938 | 200 µg/ml | $322.00 | |||
galectin-3 Antibody (M3/38) AC | sc-23938 AC | 500 µg/ml, 25% agarose | $424.00 | |||
galectin-3 Antibody (M3/38) HRP | sc-23938 HRP | 200 µg/ml | $322.00 | |||
galectin-3 Antibody (M3/38) FITC | sc-23938 FITC | 200 µg/ml | $336.00 | |||
galectin-3 Antibody (M3/38) PE | sc-23938 PE | 200 µg/ml | $349.00 | |||
galectin-3 Antibody (M3/38) Alexa Fluor® 488 | sc-23938 AF488 | 200 µg/ml | $364.00 | |||
galectin-3 Antibody (M3/38) Alexa Fluor® 546 | sc-23938 AF546 | 200 µg/ml | $364.00 | |||
galectin-3 Antibody (M3/38) Alexa Fluor® 594 | sc-23938 AF594 | 200 µg/ml | $364.00 | |||
galectin-3 Antibody (M3/38) Alexa Fluor® 647 | sc-23938 AF647 | 200 µg/ml | $364.00 | |||
galectin-3 Antibody (M3/38) Alexa Fluor® 680 | sc-23938 AF680 | 200 µg/ml | $364.00 | |||
galectin-3 Antibody (M3/38) Alexa Fluor® 790 | sc-23938 AF790 | 200 µg/ml | $364.00 |