FYB2 Antibody (G-2): sc-514947
- FYB2 Antibody (G-2) is a mouse monoclonal IgG2a κ FYB2 antibody provided at 200 µg/ml
- raised against amino acids 281-506 mapping within an internal region of FYB2 of human origin
- FYB2 Antibody (G-2) is recommended for detection of FYB2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-FYB2 Antibody (G-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for FYB2 Antibody (G-2) for WB applications. These reagents are now offered in bundles with FYB2 Antibody (G-2) (see ordering information below).
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FYB2 Antibody (G-2) is a mouse monoclonal IgG2a kappa light chain antibody that detects FYB2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FYB2 (G-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. FYB2 protein plays a crucial role in cellular signaling pathways, particularly in regulating actin cytoskeleton dynamics, which is essential for processes such as cell migration, adhesion, and overall cellular morphology. Understanding FYB2 function is important because dysregulation of actin dynamics can lead to various diseases, including cancer metastasis and developmental disorders. Additionally, FYB2 interacts with several key proteins involved in these pathways, such as actin-binding protein profilin and small GTPase Rac1, highlighting FYB2′s significance in maintaining cellular integrity and function. Anti-FYB2 antibody (G-2) effectively detects this protein across multiple species, making FYB2 (G-2) monoclonal antibody an invaluable tool for researchers studying underlying mechanisms of cell behavior and disease progression.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FYB2 Antibody (G-2) References:
- Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. | Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
- New insights into the evolution of chromosome 1. | Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
- Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody. | McClintock, D., et al. 2006. Proc Natl Acad Sci U S A. 103: 2154-9. PMID: 16461887
- Cell biology: ageing nucleus gets out of shape. | Lans, H. and Hoeijmakers, JH. 2006. Nature. 440: 32-4. PMID: 16511477
- Chromosome 1 abnormalities in multiple myeloma. | Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
- Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness. | Hennah, W., et al. 2006. Schizophr Bull. 32: 409-16. PMID: 16699061
- The DNA sequence and biological annotation of human chromosome 1. | Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
- Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1. | Watson, ML., et al. 1990. J Exp Med. 172: 263-72. PMID: 1694218
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FYB2 Antibody (G-2) | sc-514947 | 200 µg/ml | $322.00 | |||
FYB2 Antibody (G-2): m-IgG Fc BP-HRP Bundle | sc-526407 | 200 µg Ab; 10 µg BP | $361.00 | |||
FYB2 Antibody (G-2): m-IgG2a BP-HRP Bundle | sc-546628 | 200 µg Ab; 10 µg BP | $361.00 | |||
FYB2 Antibody (G-2) AC | sc-514947 AC | 500 µg/ml, 25% agarose | $424.00 | |||
FYB2 Antibody (G-2) HRP | sc-514947 HRP | 200 µg/ml | $322.00 | |||
FYB2 Antibody (G-2) FITC | sc-514947 FITC | 200 µg/ml | $336.00 | |||
FYB2 Antibody (G-2) PE | sc-514947 PE | 200 µg/ml | $349.00 | |||
FYB2 Antibody (G-2) Alexa Fluor® 488 | sc-514947 AF488 | 200 µg/ml | $364.00 | |||
FYB2 Antibody (G-2) Alexa Fluor® 546 | sc-514947 AF546 | 200 µg/ml | $364.00 | |||
FYB2 Antibody (G-2) Alexa Fluor® 594 | sc-514947 AF594 | 200 µg/ml | $364.00 | |||
FYB2 Antibody (G-2) Alexa Fluor® 647 | sc-514947 AF647 | 200 µg/ml | $364.00 | |||
FYB2 Antibody (G-2) Alexa Fluor® 680 | sc-514947 AF680 | 200 µg/ml | $364.00 | |||
FYB2 Antibody (G-2) Alexa Fluor® 790 | sc-514947 AF790 | 200 µg/ml | $364.00 |