FXR2 Antibody (A42): sc-56681
- FXR2 Antibody (A42) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against FXR2 of human origin
- recommended for detection of FXR2 of human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FXR2 Antibody (A42). This work is in progress.
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FXR2 Antibody (A42) is a mouse monoclonal IgG1 antibody that detects FXR2 in human samples through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF) applications. FXR2, a member of the fragile X family of proteins, plays a crucial role in the regulation of mRNA translation and stability, which is vital for proper neuronal function and development. FXR2 is predominantly located in the cytoplasm, where FXR2 associates with polyribosomes, facilitating the translation of specific mRNAs that are essential for synaptic plasticity and cognitive function. The interaction of FXR2 with FXR1 and FMRP homologs is particularly important as these proteins form heterodimers that can influence the transport and localization of mRNAs within neurons, thereby impacting synaptic development and function. FXR2′s presence in both the cytoplasm and nucleus, along with FXR2′s ability to bind RNA, underscores FXR2′s significance in the post-transcriptional regulation of gene expression, making FXR2 a critical player in the molecular mechanisms underlying fragile X syndrome and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FXR2 Antibody (A42) | sc-56681 | 100 µg/ml | $322.00 |