Follicular DC Marker Antibody (Ki-M9R): sc-58529
- Follicular DC Marker Antibody (Ki-M9R) is a mouse monoclonal IgG1 Follicular DC Marker antibody, cited in 1 publications, provided at 100 µg/ml
- raised against peritoneal macrophages of rat origin
- recommended for detection of antigen trapping macrophages of the B-cell system such as sinus lining cells and dendritic reticulum cells of mouse and rat origin by IF and IHC(P); may cross-react with splenic metallophils; non cross-reactive with macrophages in T-cell areas and macrophages in nonlymphoid organs
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Follicular DC Marker Antibody (Ki-M9R). This work is in progress.
QUICK LINKS
SEE ALSO...
Follicular DC Marker Antibody (Ki-M9R) is a mouse monoclonal IgG1 antibody that detects Follicular DC Marker protein in mouse and rat samples through immunofluorescence (IF) and immunohistochemistry. Anti-Follicular DC Marker antibody (Ki-M9R) is available in non-conjugated format. Dendritic cells (DCs) play a crucial role in the immune system, particularly in processing and presenting antigens to T cells, which is essential for initiating adaptive immune responses. Among various dendritic cell types, Follicular DCs primarily reside in germinal centers of lymphoid follicles, where these cells facilitate B cell selection and maturation. This specific localization is vital for developing effective humoral immunity, as Follicular DCs provide essential signals and support for B cell activation and differentiation. Follicular DCs retain and present antigens over extended periods, which is critical for forming long-lasting immunological memory. Follicular DC Marker antibody (Ki-M9R) serves as an invaluable tool for researchers studying dendritic cell function dynamics and interactions within the immune microenvironment.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Follicular DC Marker Antibody (Ki-M9R) References:
- Follicular dendritic cells in aging, a 'bottle-neck' in the humoral immune response. | Aydar, Y., et al. 2004. Ageing Res Rev. 3: 15-29. PMID: 15163101
- Role of follicular dendritic cells in the early HIV-1 infection: in vitro model without specific antibody. | Taruishi, M., et al. 2004. Microbiol Immunol. 48: 693-702. PMID: 15383706
- Follicular dendritic cells produce IL-15 that enhances germinal center B cell proliferation in membrane-bound form. | Park, CS., et al. 2004. J Immunol. 173: 6676-83. PMID: 15557159
- How do follicular dendritic cells interact intimately with B cells in the germinal centre? | Park, CS. and Choi, YS. 2005. Immunology. 114: 2-10. PMID: 15606789
- Sonic hedgehog is produced by follicular dendritic cells and protects germinal center B cells from apoptosis. | Sacedón, R., et al. 2005. J Immunol. 174: 1456-61. PMID: 15661904
- Human follicular dendritic cells express prostacyclin synthase: a novel mechanism to control T cell numbers in the germinal center. | Lee, IY., et al. 2005. J Immunol. 175: 1658-64. PMID: 16034106
- Growth pattern and distribution of follicular dendritic cells in mantle cell lymphoma: a clinicopathological study of 96 patients. | Schrader, C., et al. 2006. Virchows Arch. 448: 151-9. PMID: 16133361
- Taking control of follicular dendritic cells. | Chaplin, DD. and Zindl, CL. 2006. Immunity. 24: 13-5. PMID: 16413918
- The rationale for B lymphocyte depletion in Graves' disease. Monoclonal anti-CD20 antibody therapy as a novel treatment option. | El Fassi, D., et al. 2006. Eur J Endocrinol. 154: 623-32. PMID: 16645007
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Follicular DC Marker Antibody (Ki-M9R) | sc-58529 | 100 µg/ml | $316.00 |