Molecular structure of Folic Acid, CAS Number: 59-30-3
Folic Acid (CAS 59-30-3)
See product citations (2)
Alternate Names:
Pteroylglutamic acid
Application:
Folic Acid is an important cofactor in the transfer of one-carbon moieties plays role in formation of S-adenosyl met
CAS Number:
59-30-3
Purity:
≥98%
Molecular Weight:
441.4
Molecular Formula:
C19H19N7O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Folic acid, also known as vitamin B9, is a vital nutrient that is indispensable for the growth and development of cells within the human body. It plays a role in the metabolic cycle of cells and actively participates in the synthesis of essential biomolecules like DNA, RNA, and proteins. This valuable nutrient can be naturally obtained from various food sources, including dark green leafy vegetables, legumes, and fortified breakfast cereals. Within the body, folic acid undergoes a series of enzymatic reactions that facilitate its metabolism. These reactions culminate in the conversion of folic acid into its active form known as tetrahydrofolic acid. Subsequently, this active form of folic acid actively contributes to the synthesis of biomolecules such as DNA, RNA, and proteins, sustaining the overall cellular processes.
Folic Acid (CAS 59-30-3) References
- Dictyostelium discoideum: a model host to measure bacterial virulence. | Froquet, R., et al. 2009. Nat Protoc. 4: 25-30. PMID: 19131953
- Plasma FGF23 levels increase rapidly after acute kidney injury. | Christov, M., et al. 2013. Kidney Int. 84: 776-85. PMID: 23657144
- Structural basis for molecular recognition of folic acid by folate receptors. | Chen, C., et al. 2013. Nature. 500: 486-9. PMID: 23851396
- Folates Induce Colorectal Carcinoma HT29 Cell Line Proliferation Through Notch1 Signaling. | Rodriguez, JM., et al. 2015. Nutr Cancer. 67: 706-11. PMID: 25802929
- Novel Water-Borne Polyurethane Nanomicelles for Cancer Chemotherapy: Higher Efficiency of Folate Receptors Than TRAIL Receptors in a Cancerous Balb/C Mouse Model. | Ajorlou, E., et al. 2016. Pharm Res. 33: 1426-39. PMID: 26908046
- Surface-enhanced Raman spectroscopy of cell lysates mixed with silver nanoparticles for tumor classification. | Hassoun, M., et al. 2017. Beilstein J Nanotechnol. 8: 1183-1190. PMID: 28685119
- Fibroblast Growth Factor 23 Expression Is Increased in Multiple Organs in Mice With Folic Acid-Induced Acute Kidney Injury. | Egli-Spichtig, D., et al. 2018. Front Physiol. 9: 1494. PMID: 30405444
- Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation. | Ferrè, S., et al. 2019. Kidney Int. 96: 1359-1373. PMID: 31601454
- Vitamin B12 and folic acid alleviate symptoms of nutritional deficiency by antagonizing aryl hydrocarbon receptor. | Kim, DJ., et al. 2020. Proc Natl Acad Sci U S A. 117: 15837-15845. PMID: 32571957
- Inhibiting Neddylation with MLN4924 Suppresses Growth and Delays Multicellular Development in Dictyostelium discoideum. | Huber, RJ., et al. 2021. Biomolecules. 11: PMID: 33807046
- CPT1α maintains phenotype of tubules via mitochondrial respiration during kidney injury and repair. | Yuan, Q., et al. 2021. Cell Death Dis. 12: 792. PMID: 34392303
- Characterization of backbone dynamics using solution NMR spectroscopy to discern the functional plasticity of structurally analogous proteins. | Kawale, AA. and Burmann, BM. 2021. STAR Protoc. 2: 100919. PMID: 34761231
- Comparison of CD34+ bone marrow cells purified by immunomagnetic and immunoadsorption cell separation techniques. | Firat, H., et al. 1998. Bone Marrow Transplant. 21: 933-8. PMID: 9613787
Inhibitor of:
AHCYL1, C8A, CCDC162, DGCR2, FAM123A, FTSJ1, HAL, HGD, HIV-1 Nef, LSAMP, METTL2A, MTHFS, PCMTD1, RPESP, SLC48A1, SPATA25, STOX1, SULT1A4, Tra-2β, and Zic4.Activator of:
α-dystroglycan, α-FR, 1110037F02Rik, 2310079F23Rik, 2810422O20Rik, 4832428D23Rik, 5-Methylcytidine, 5830415F09Rik, 8D6, ACOT8, ADAT2, ADH5, AdoMetDC, AdSS1, AF9, AGAT, AGXT, AGXT2L1, AHCYL2, AICAR transformylase, ALDH1L1, ALG3, ALX1, AMT, ANKRD13D, ApoER2, Aprataxin, ASMTL, Ataxin-7, atrophin-1, B630005N14Rik, BBOX1, BC023814, BEND5, BHMT, BHMT2, Biotin, biotinidase, C20orf165, C7orf73, C8orf79_6430573F11Rik, cadherin-7, CBR4, CBS, CBX7, CCDC134, Cdt1, CDY2, CHDH, ChoKB, CHPT1, CRELD1, CTNNBL1, CYBRD1, cystatin D, cyt19, DDAH I, DGCR2, DGCR6L, DHFRL1, Dim1, DIMT1, DMGDH, DMRTB1, Dmrtc1b, DMXL2, DNA pol δ cat, DNAJC25-GNG10, Dnmt1, Dnmt2, Dnmt3L, Dopey-1, DOT1, DOT1L1, DPH5, DPYD, DSCR 3, dUTPase, DUX5, E2F-5, EBP2, EF-1 α1, Epigen, Erythroid lineage, EVC, FAM123A, FHR-1, Fibrillarin-like 1, Formate Dehydrogenase, FOXD4L3, FTSJ3, GalNAc-T13, GalNAc-T3, GAMT, GART, Gatm, GGH, GHR, GIF, GLDC, GLOD4, Glucose-6-Phosphate Dehydrogenase, GlyT1, GMPPB, GNMT, GPC3, GPR157, GPR161, GSC2, GSH-2, H2-Kb, HCP1, HEMK2, Hemoglobin δ, HHIPL1, Histone cluster 1 H1E, Histone cluster 1 H2AB, Histone cluster 3 H2A, HMG-2L1, HNMT, HORMAD2, HoxA13, HoxA6, HoxA7, HoxB1, HoxB2, HoxB3, HoxB6, HoxC10, HoxC11, HoxD11, HTF9C, HYLS1, IgG2, ISX, IZUMO1, JMJD3, Keratin 24, KIAA1429, KRTAP19-3, KRTAP9-1, Krtap9-5, LCMT1, LEKR1_Lekr1, LOC100040307, LOC644192, LOC645323, LRP1B, LTrp7, lysine, MAB21L1, Mammaglobin B, MAT I, MAT Iα, MAT IIα, MAT IIβ, MAT III, MBD5, MEM Vitamins, METT10D, METTL1, METTL10, METTL11A, METTL11B, METTL2, METTL23, METTL25, METTL2A, METTL2B, METTL3, METTL4, METTL5, METTL6, METTL9, MGP, MLL3, MOCS3, MRI1, MS4A4A, mSHMT, MSR, Msx-1, MTHFD1L, MTHFD2, MTHFD2L, MTHFR, MTHFSD, MTR, MTRR, Muscle Actin, MYH14, Nanos3, NANS, NAT-8L, neogenin, NNMT, NOMO, NOMO2, Nop58, NOSIP, Notch 1, Notum, NSUN1, NSUN2, NSUN5, NSUN5B, NSUN5C, NSUN7, NT5DC1, ODF3B, OGFOD3, Olfr15, OR5BU1, OR5H6, OR5K4, OR6N2, OSAP, PANK1, PANK4, Papilin, Pax-9, PCBD2, PCDHA11, PCDHA12, PCDHA6, PCDHAC1_Pcdhac1, PCDHAC2_Pcdhac2, PCDHGA4, PCDHGA5, PCDHGA6, PCIF1, PCMTD1, PCMTD2, PDF, Peg12, PEPD, PGDH, PIG-F, PIG-N, PIG-X, PIWI, PIWIL4, Placental lactogen I, Placental lactogen II, PLET1, Pneumocystis carinii, PORCN, POTE8, POTEJ, PPC Synthetase, PRAME like-4, Pregnancy Zone protein, PRMT1, PRMT10, PRMT2, PRMT3, PRMT6, PRMT7, Prohibitin 2, protein 4.2, PRPS2, PRTFDC1, PSG1, Psg17, Psg19, PSG3, PSG6, PSG8, PSS1, PTPN13LY, PTPS, QDPR, Rad54B, RAI1, RASSF1A, RBKS, RBM Y chromosome, RBMY1A1, RG9MTD2, RGL2, RhCE, RNase H1, robo1, ROPN1, ROPN1B, RTP2, SAHH, SAHH-3, SAMC, SAP 130, sarcosine dehydrogenase, SBZF3, SDS3, Selenium, Selenoprotein M marker, SEMA4C, SHOX, SHOX2B, Siglec-E, SLC41A1, SLC6A15, Sm B/B′, SMCP, SMYD2, SMYD4, SNURF, Sox-13, Sox-18, SPACA7, SPANX-A-E, SPANX-N4, SPATA12, SPATA25, SPATA9, SPERT, SPNR, SPR, SPR-5, Sptrx-2, SULT1C3, Tankyrase-1, TBR-1, TEX29, TEX30, THAP8, THNSL2, THTR2, TNP1, Tns2, Tomt, TPH, TPH2, Transcobalamin I, Treacle, TRF1, TRM12, TRMT1, TRMT112, Trmt2b, TRMT5, TRMT6, TRMT61B, Trp E, TS, TTC13, TUSC3, Txl-2, TYW1B, UNC-2, UPIa, VAX1, VCX-B, VCX-C, VSTM3, Wnt-7a, Ythdc1, YTHDF3, ZC3H13, ZCCHC6, ZFP37, ZIM3, ZNF407, ZNF436, ZNF649, ZNRF1, and Zonadhesin.Substrate of:
DHFR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Folic Acid, 10 g | sc-204758 | 10 g | $72.00 |