FNBP2 Antibody (G-10): sc-398399
- FNBP2 Antibody (G-10) is a mouse monoclonal IgG1 κ FNBP2 antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1038-1060 at the C-terminus of FNBP2 of human origin
- FNBP2 Antibody (G-10) is recommended for detection of FNBP2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-FNBP2 Antibody (G-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for FNBP2 Antibody (G-10) for WB applications. These reagents are now offered in bundles with FNBP2 Antibody (G-10) (see ordering information below).
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FNBP2 Antibody (G-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects FNBP2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FNBP2 (G-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FNBP2, also known as formin binding protein 2, SRGAP3, ARHGAP34, or SRGAP2, is a 1,071 amino acid protein that plays a crucial role in cellular signaling pathways. FNBP2 is primarily expressed at low levels in the placenta, kidney, and ovary, and contains a FCH (Fps/Fes/Fer/CIP4 homology) domain, a Rho-GAP domain, and a SH3 (Src homology 3) domain, which are essential for its function as a putative GTPase-activating protein for Rho family small GTPases. These Rho GTPases act as molecular switches that regulate vital cellular processes such as actin dynamics, cell adhesion, cell-cycle progression, and transcription. FNBP2′s interaction with other proteins, including members of the FNBP2 family like SRGAP1, WRP (WAVE-associated Rac GTPase-activating protein), and ARHGAP4, suggests involvement in critical processes such as cell migration and axon guidance, making FNBP2 an important target for research in cellular biology and developmental processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FNBP2 Antibody (G-10) References:
- Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway. | Wong, K., et al. 2001. Cell. 107: 209-21. PMID: 11672528
- FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains. | Katoh, M. and Katoh, M. 2003. Int J Mol Med. 11: 791-7. PMID: 12736724
- Identification and characterization of human DIAPH3 gene in silico. | Katoh, M. and Katoh, M. 2004. Int J Mol Med. 13: 473-8. PMID: 14767582
- Identification and characterization of human FCHSD1 and FCHSD2 genes in silico. | Katoh, M. and Katoh, M. 2004. Int J Mol Med. 13: 749-54. PMID: 15067381
- Identification and characterization of the human FMN1 gene in silico. | Katoh, M. and Katoh, M. 2004. Int J Mol Med. 14: 121-6. PMID: 15202026
- Identification and characterization of human ARHGAP23 gene in silico. | Katoh, M. and Katoh, M. 2004. Int J Oncol. 25: 535-40. PMID: 15254754
- Identification and characterization of human FCHO2 and mouse Fcho2 genes in silico. | Katoh, M. and Katoh, M. 2004. Int J Mol Med. 14: 327-31. PMID: 15254787
- Characterization of FMN2 gene at human chromosome 1q43. | Katoh, M. and Katoh, M. 2004. Int J Mol Med. 14: 469-74. PMID: 15289902
- Characterization of RUSC1 and RUSC2 genes in silico. | Katoh, M. and Katoh, M. 2004. Oncol Rep. 12: 933-8. PMID: 15375525
- Characterization of human ARHGAP10 gene in silico. | Katoh, M. and Katoh, M. 2004. Int J Oncol. 25: 1201-6. PMID: 15375573
- Identification and characterization of ARHGAP27 gene in silico. | Katoh, Y. and Katoh, M. 2004. Int J Mol Med. 14: 943-7. PMID: 15492870
- Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. | Chan, DC., et al. 1996. EMBO J. 15: 1045-54. PMID: 8605874
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FNBP2 Antibody (G-10) | sc-398399 | 200 µg/ml | $316.00 | |||
FNBP2 Antibody (G-10): m-IgG Fc BP-HRP Bundle | sc-527773 | 200 µg Ab; 10 µg BP | $354.00 | |||
FNBP2 Antibody (G-10): m-IgG1 BP-HRP Bundle | sc-533146 | 200 µg Ab; 20 µg BP | $354.00 | |||
FNBP2 Antibody (G-10) AC | sc-398399 AC | 500 µg/ml, 25% agarose | $416.00 | |||
FNBP2 Antibody (G-10) HRP | sc-398399 HRP | 200 µg/ml | $316.00 | |||
FNBP2 Antibody (G-10) FITC | sc-398399 FITC | 200 µg/ml | $330.00 | |||
FNBP2 Antibody (G-10) PE | sc-398399 PE | 200 µg/ml | $343.00 | |||
FNBP2 Antibody (G-10) Alexa Fluor® 488 | sc-398399 AF488 | 200 µg/ml | $357.00 | |||
FNBP2 Antibody (G-10) Alexa Fluor® 546 | sc-398399 AF546 | 200 µg/ml | $357.00 | |||
FNBP2 Antibody (G-10) Alexa Fluor® 594 | sc-398399 AF594 | 200 µg/ml | $357.00 | |||
FNBP2 Antibody (G-10) Alexa Fluor® 647 | sc-398399 AF647 | 200 µg/ml | $357.00 | |||
FNBP2 Antibody (G-10) Alexa Fluor® 680 | sc-398399 AF680 | 200 µg/ml | $357.00 | |||
FNBP2 Antibody (G-10) Alexa Fluor® 790 | sc-398399 AF790 | 200 µg/ml | $357.00 | |||
FNBP2 (G-10) Neutralizing Peptide | sc-398399 P | 100 µg/0.5 ml | $68.00 |