FMNL2 Antibody (D-3): sc-390298
- FMNL2 Antibody (D-3) is a mouse monoclonal IgG1 κ FMNL2 antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 461-505 mapping within an internal region of FMNL2 of human origin
- FMNL2 Antibody (D-3) is recommended for detection of FMNL2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-FMNL2 Antibody (D-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for FMNL2 Antibody (D-3) for WB and IHC(P) applications. These reagents are now offered in bundles with FMNL2 Antibody (D-3) (see ordering information below).
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FMNL2 Antibody (D-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects FMNL2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). FMNL2 (D-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Formin-like protein 2 (FMNL2), also known as Formin homology 2 domain-containing protein 2 or FHOD2, is a 1,087 amino acid protein encoded by the human gene FMNL2. FMNL2 is a member of the formin homology family, characterized by the presence of one diaphanous autoregulatory domain, one formin homology 2 domain, and one Rho GTPase-binding/formin homology 3 domain. Formins are essential for the formation of actin-based structures within cells, playing critical roles in processes such as morphogenesis, cytokinesis, and cell polarity. FMNL2 is involved in the regulation of cell motility and the survival of macrophages, which is crucial for immune response and tissue homeostasis. FMNL2′s ability to interact with specific proteins, such as Rho GTPases, further underscores its importance in cellular dynamics and signaling pathways, making anti-FMNL2 antibody (D-3) a valuable tool for researchers studying these processes in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FMNL2 Antibody (D-3) References:
- FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages. | Yayoshi-Yamamoto, S., et al. 2000. Mol Cell Biol. 20: 6872-81. PMID: 10958683
- Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico. | Katoh, M. and Katoh, M. 2003. Int J Oncol. 22: 1161-8. PMID: 12684686
- The mouse formin, FRLalpha, slows actin filament barbed end elongation, competes with capping protein, accelerates polymerization from monomers, and severs filaments. | Harris, ES., et al. 2004. J Biol Chem. 279: 20076-87. PMID: 14990563
- Identification and characterization of the human FMN1 gene in silico. | Katoh, M. and Katoh, M. 2004. Int J Mol Med. 14: 121-6. PMID: 15202026
- High expression of FMNL1 protein in T non-Hodgkin's lymphomas. | Favaro, PM., et al. 2006. Leuk Res. 30: 735-8. PMID: 16494944
- Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse. | Gomez, TS., et al. 2007. Immunity. 26: 177-90. PMID: 17306570
- Formin the way. | Schwartzberg, PL. 2007. Immunity. 26: 139-41. PMID: 17307700
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FMNL2 Antibody (D-3) | sc-390298 | 200 µg/ml | $322.00 | |||
FMNL2 Antibody (D-3): m-IgG Fc BP-HRP Bundle | sc-527623 | 200 µg Ab; 10 µg BP | $361.00 | |||
FMNL2 Antibody (D-3): m-IgG1 BP-HRP Bundle | sc-532996 | 200 µg Ab; 20 µg BP | $361.00 | |||
FMNL2 Antibody (D-3) AC | sc-390298 AC | 500 µg/ml, 25% agarose | $424.00 | |||
FMNL2 Antibody (D-3) HRP | sc-390298 HRP | 200 µg/ml | $322.00 | |||
FMNL2 Antibody (D-3) FITC | sc-390298 FITC | 200 µg/ml | $336.00 | |||
FMNL2 Antibody (D-3) PE | sc-390298 PE | 200 µg/ml | $349.00 | |||
FMNL2 Antibody (D-3) Alexa Fluor® 488 | sc-390298 AF488 | 200 µg/ml | $364.00 | |||
FMNL2 Antibody (D-3) Alexa Fluor® 546 | sc-390298 AF546 | 200 µg/ml | $364.00 | |||
FMNL2 Antibody (D-3) Alexa Fluor® 594 | sc-390298 AF594 | 200 µg/ml | $364.00 | |||
FMNL2 Antibody (D-3) Alexa Fluor® 647 | sc-390298 AF647 | 200 µg/ml | $364.00 | |||
FMNL2 Antibody (D-3) Alexa Fluor® 680 | sc-390298 AF680 | 200 µg/ml | $364.00 | |||
FMNL2 Antibody (D-3) Alexa Fluor® 790 | sc-390298 AF790 | 200 µg/ml | $364.00 |