Filamin 1 Antibody (3F180): sc-71118
- Filamin 1 Antibody (3F180) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against full length platelet Filamin 1 of human origin
- recommended for detection of Filamin 1 from platelets, lymphocytes, fibroblasts and smooth muscle of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See Filamin 1 (E-3): sc-17749 for Filamin 1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Filamin 1 Antibody (3F180) for WB and IHC(P) applications. These reagents are now offered in bundles with Filamin 1 Antibody (3F180) (see ordering information below).
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Filamin 1 Antibody (3F180) is a mouse monoclonal IgG1 antibody that detects Filamin 1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Filamin 1 is a crucial actin-binding protein that plays a significant role in maintaining the structural integrity of the cytoskeleton by crosslinking actin filaments into a three-dimensional network, which is essential for cellular shape, motility, and mechanical stability. Filamin 1 is predominantly found in the cytoplasm, where Filamin 1 forms homodimers that facilitate the organization of actin filaments, thereby influencing cell signaling and migration. Proper functioning of Filamin 1 is vital for various cellular processes, including the maintenance of cell shape and the regulation of cell adhesion, which are critical for tissue integrity and function. Dysregulation of Filamin 1 has been implicated in several diseases, including cancer and cardiovascular disorders, highlighting Filamin 1′s importance as a target for therapeutic intervention. Anti-Filamin 1 antibody (3F180) provides a reliable tool for researchers aiming to explore the dynamics of actin cytoskeleton organization and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Filamin 1 Antibody (3F180) | sc-71118 | 200 µg/ml | $322.00 | |||
Filamin 1 Antibody (3F180): m-IgG Fc BP-HRP Bundle | sc-539348 | 200 µg Ab; 10 µg BP | $361.00 | |||
Filamin 1 Antibody (3F180): m-IgG1 BP-HRP Bundle | sc-541429 | 200 µg Ab; 20 µg BP | $361.00 |