
Fibronectin Antibody (616) is a mouse monoclonal IgG3 antibody that detects Fibronectin in human and porcine samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Fibronectin is a crucial extracellular matrix glycoprotein that plays a significant role in cell adhesion, motility, and wound healing, making anti-Fibronectin antibody (616) essential for studying tissue repair and regeneration. This high molecular weight heterodimeric protein is found on most cell surfaces, extracellular fluids, and plasma, highlighting widespread importance in physiological processes. Fibronectin′s structure is characterized by multiple domains that facilitate interactions with other proteins and cells, vital for maintaining extracellular matrix integrity and promoting cellular communication. Alternative splicing and glycosylation of Fibronectin lead to various isoforms, some associated with specific tissues or pathological conditions, such as malignancies. Notably, glycosylated Fibronectin and splice variants have been linked to myofibroblast phenotype formation in Dupuytren′s disease, underscoring Fibronectin′s relevance in both normal physiology and disease states. Fibronectin monoclonal antibody (616) serves as an invaluable tool for researchers studying these complex biological processes and Fibronectin′s role in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibronectin Antibody (616) | sc-81767 | 200 µg/ml | $322.00 | |||
Fibronectin Antibody (616): m-IgGκ BP-HRP Bundle | sc-534490 | 200 µg Ab; 40 µg BP | $361.00 |