Fibronectin Antibody (2755-8): sc-69681

Fibronectin Antibody (2755-8) is a mouse monoclonal IgG1 antibody that detects Fibronectin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-Fibronectin antibody (2755-8) plays a crucial role in understanding the dynamics of the extracellular matrix, as Fibronectin is a high molecular weight heterodimeric glycoprotein essential for various cellular functions, including cell adhesion, motility, and wound healing. Fibronectin is primarily located in the extracellular matrix and on cell surfaces, where Fibronectin facilitates interaction between cells and their environment, thereby influencing tissue repair and development. Notably, Fibronectin′s ability to undergo alternative splicing and glycosylation results in multiple isoforms, some associated with specific tissues or pathological conditions, such as malignancies. For instance, glycosylated Fibronectin and splice variants have been linked to the myofibroblast phenotype in Dupuytren′s disease, highlighting Fibronectin′s importance in both normal physiology and disease states. Fibronectin monoclonal antibody (2755-8) enables researchers to gain valuable insights into Fibronectin′s roles in various biological processes and implications in health and disease.

The preferred Fibronectin antibody is Fibronectin Antibody (EP5): sc-8422.