Fibrinogen β Antibody (E-5): sc-271018

Fibrinogen β Antibody (E-5) is a mouse monoclonal IgG1 antibody that detects Fibrinogen β in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Fibrinogen β is one of the three subunits of the plasma glycoprotein Fibrinogen, which plays a crucial role in the coagulation cascade, particularly in the formation of Fibrin, the primary component of blood clots. Fibrinogen β is synthesized in the liver and is essential for platelet aggregation, which is vital for hemostasis following tissue injury. The Fibrinogen β subunit not only contributes to the structural integrity of Fibrin but also influences Fibrinogen′s interactions with other coagulation factors and cellular components. Notably, Fibrinogen β can undergo post-translational modifications, such as phosphorylation and glycosylation, which can affect function and stability, thereby impacting the overall coagulation process. Understanding these modifications is important as they can alter Fibrinogen β′s activity and interactions with other molecules, potentially influencing pathological conditions such as thrombosis and inflammation. Anti-Fibrinogen β antibody (E-5) is an invaluable tool for researchers studying coagulation mechanisms and related disorders.

The preferred Fibrinogen β antibody is Fibrinogen β Antibody (D-4): sc-271035.