Fibrinogen Antibody (GMA-035): sc-65966
- Fibrinogen Antibody (GMA-035) is a mouse monoclonal IgG1, cited in 3 publications, provided at 100 µg/ml
- raised against Fibrinogen of human origin
- recommended for detection of whole Fibrinogen, consisting of a dimer of three pairs of non-identical chains, α, β and γ, of human origin by WB; may cross-react with fibrin degredation products
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Fibrinogen Antibody (GMA-035). This work is in progress.
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Fibrinogen Antibody (GMA-035) is a mouse monoclonal IgG1 antibody that detects Fibrinogen in human samples by western blotting (WB). Fibrinogen is a crucial plasma glycoprotein synthesized in the liver, consisting of three structurally distinct subunits: α, β, and γ. Fibrinogen (GMA-035) antibody recognizes a protein that plays a vital role in the coagulation cascade, particularly in platelet aggregation and Fibrin formation, which is essential for blood clotting. Fibrinogen′s importance extends beyond structural roles; anti-Fibrinogen antibody (GMA-035) targets a protein involved in regulating plasma viscosity and erythrocyte aggregation, making Fibrinogen a key player in maintaining hemostasis. Following vascular injury, Fibrinogen is cleaved by Thrombin to produce Fibrin, the primary component of blood clots. The cleavage products of Fibrinogen not only facilitate cell adhesion and spreading but also exhibit vasoconstrictor and chemotactic properties, acting as mitogens for various cell types. Fibrinogen monoclonal antibody (GMA-035) serves as an invaluable tool for researchers studying coagulation processes and related pathologies, providing insights into the dynamics of hemostasis and Fibrinogen′s role in various physiological and pathological conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibrinogen Antibody (GMA-035) | sc-65966 | 100 µg/ml | $322.00 |