Fibrinogen Antibody (6G12): sc-51898
- Fibrinogen Antibody (6G12) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against fibrin degradation products of human origin
- recommended for detection of whole Fibrinogen, consisting of a dimer of three pairs of non-identical chains, α, β and γ, and Fibrin degradation products of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Fibrinogen Antibody (6G12). This work is in progress.
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Fibrinogen Antibody (6G12) is a mouse monoclonal IgG1 antibody that detects Fibrinogen in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Fibrinogen is a crucial plasma glycoprotein synthesized in the liver, consisting of three distinct subunits: α, β, and γ. Fibrinogen plays a vital role in the coagulation cascade, particularly in platelet aggregation and the formation of Fibrin, which is essential for blood clotting and maintaining hemostasis following tissue injury. Upon vascular damage, Fibrinogen is cleaved by Thrombin, resulting in the formation of Fibrin, the primary component of blood clots. The cleavage products of Fibrinogen not only facilitate cell adhesion and spreading but also exhibit vasoconstrictor and chemotactic properties, acting as mitogens for various cell types. Fibrinogen′s ability to regulate these processes underscores its importance in both normal physiological functions and pathological conditions, making anti-Fibrinogen antibody (6G12) an invaluable tool for researchers studying coagulation and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibrinogen Antibody (6G12) | sc-51898 | 100 µg/ml | $322.00 |