FHL-1 Antibody (L9-42): sc-101046
- FHL-1 Antibody (L9-42) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against recombinant FHL-1 of human origin
- recommended for detection of FHL-1 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FHL-1 Antibody (L9-42). This work is in progress.
QUICK LINKS
FHL-1 Antibody (L9-42) is a mouse monoclonal IgG2a antibody that detects FHL-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). FHL-1, a member of the four-and-a-half-LIM domain protein family, plays a crucial role in muscle development and function, particularly in skeletal and cardiac muscle, where FHL-1 is expressed at significantly higher levels compared to smooth muscle tissues. FHL-1′s localization in the cytosol of myoblasts, myotubes, and differentiated myocytes is essential for function, as FHL-1 facilitates the regulation of gene expression through interactions with transcription factors like CREB and CREM. This cytosolic presence allows FHL-1 to participate in signaling pathways that are vital for muscle differentiation and regeneration. Additionally, the unique structural features of FHL-1, including a single zinc finger domain, distinguish FHL-1 from other LIM-only proteins and contribute to specific functional interactions within the cell. FHL-1′s ability to selectively activate transcription factors underscores importance in muscle biology and highlights potential as a target for therapeutic interventions in muscle-related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FHL-1 Antibody (L9-42) | sc-101046 | 100 µg/ml | $333.00 |