FGGY Antibody (C-9): sc-393376
- FGGY Antibody (C-9) is a mouse monoclonal IgG1 κ FGGY antibody provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of FGGY of human origin
- FGGY Antibody (C-9) is recommended for detection of FGGY of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-FGGY Antibody (C-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for FGGY Antibody (C-9) for WB applications. These reagents are now offered in bundles with FGGY Antibody (C-9) (see ordering information below).
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SEE ALSO...
FGGY Antibody (C-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects FGGY protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FGGY (C-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FGGY protein, also known as FLJ10986, is a 551 amino acid member of the FGGY kinase family, which plays a crucial role in carbohydrate metabolism by phosphorylating sugars, facilitating their utilization in energy production and biosynthesis. This function links carbohydrate metabolism to energy homeostasis, impacting cellular functions and overall organismal health. FGGY is expressed in various tissues, including lung, kidney, small intestine, liver, and fetal brain, and is encoded by a gene located on chromosome 1. Mutations in FGGY have been associated with sporadic amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disorder that leads to progressive degeneration of motor neurons and ultimately results in fatal paralysis, typically within 2 to 5 years of diagnosis. FGGY′s location on chromosome 1, the largest human chromosome, highlights significance, as this chromosome harbors approximately 3,000 genes, many of which are implicated in various genetic diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FGGY Antibody (C-9) References:
- Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. | Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
- New insights into the evolution of chromosome 1. | Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
- Chromosome 1 abnormalities in multiple myeloma. | Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
- Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness. | Hennah, W., et al. 2006. Schizophr Bull. 32: 409-16. PMID: 16699061
- The DNA sequence and biological annotation of human chromosome 1. | Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
- Whole-genome analysis of sporadic amyotrophic lateral sclerosis. | Dunckley, T., et al. 2007. N Engl J Med. 357: 775-88. PMID: 17671248
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FGGY Antibody (C-9) | sc-393376 | 200 µg/ml | $322.00 | |||
FGGY Antibody (C-9): m-IgG Fc BP-HRP Bundle | sc-527683 | 200 µg Ab; 10 µg BP | $361.00 | |||
FGGY Antibody (C-9): m-IgG1 BP-HRP Bundle | sc-533056 | 200 µg Ab; 20 µg BP | $361.00 | |||
FGGY Antibody (C-9) AC | sc-393376 AC | 500 µg/ml, 25% agarose | $424.00 | |||
FGGY Antibody (C-9) HRP | sc-393376 HRP | 200 µg/ml | $322.00 | |||
FGGY Antibody (C-9) FITC | sc-393376 FITC | 200 µg/ml | $336.00 | |||
FGGY Antibody (C-9) PE | sc-393376 PE | 200 µg/ml | $349.00 | |||
FGGY Antibody (C-9) Alexa Fluor® 488 | sc-393376 AF488 | 200 µg/ml | $364.00 | |||
FGGY Antibody (C-9) Alexa Fluor® 546 | sc-393376 AF546 | 200 µg/ml | $364.00 | |||
FGGY Antibody (C-9) Alexa Fluor® 594 | sc-393376 AF594 | 200 µg/ml | $364.00 | |||
FGGY Antibody (C-9) Alexa Fluor® 647 | sc-393376 AF647 | 200 µg/ml | $364.00 | |||
FGGY Antibody (C-9) Alexa Fluor® 680 | sc-393376 AF680 | 200 µg/ml | $364.00 | |||
FGGY Antibody (C-9) Alexa Fluor® 790 | sc-393376 AF790 | 200 µg/ml | $364.00 |