FGF-17 Antibody (B-4): sc-376056
- FGF-17 Antibody (B-4) is a mouse monoclonal IgG1 κ FGF-17 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 183-215 near the C-terminus of FGF-17 of human origin
- FGF-17 Antibody (B-4) is recommended for detection of precursor and mature FGF-17 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-FGF-17 Antibody (B-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for FGF-17 Antibody (B-4) for WB and IHC(P) applications. These reagents are now offered in bundles with FGF-17 Antibody (B-4) (see ordering information below).
FGF-17 Antibody (B-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects FGF-17 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). FGF-17 (B-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FGF-17, a member of the fibroblast growth factor (FGF) family, plays a critical role in regulating cell growth, differentiation, and embryonic development, particularly within the central nervous system and limb structures. FGF-17 is primarily located in the extracellular space, where FGF-17 interacts with fibroblast growth factor receptors (FGFRs) to initiate signaling cascades that promote cellular proliferation and survival. This extracellular localization allows FGF-17 to influence neighboring cells, impacting tissue development and repair processes. Precise regulation of FGF-17 expression during embryogenesis highlights FGF-17′s importance in organogenesis and complex structure formation. Aberrations in FGF-17 signaling pathways have been implicated in various neurological disorders, making FGF-17 a significant target for therapeutic research.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FGF-17 Antibody (B-4) References:
- Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin. | Mansukhani, A., et al. 1992. Proc Natl Acad Sci U S A. 89: 3305-9. PMID: 1373495
- Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors. | Dionne, CA., et al. 1990. EMBO J. 9: 2685-92. PMID: 1697263
- Recent developments in the cell biology of basic fibroblast growth factor. | Rifkin, DB. and Moscatelli, D. 1989. J Cell Biol. 109: 1-6. PMID: 2545723
- Structure and expression of a novel fibroblast growth factor, FGF-17, preferentially expressed in the embryonic brain. | Hoshikawa, M., et al. 1998. Biochem Biophys Res Commun. 244: 187-91. PMID: 9514906
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FGF-17 Antibody (B-4) | sc-376056 | 200 µg/ml | $316.00 | |||
FGF-17 Antibody (B-4): m-IgG Fc BP-HRP Bundle | sc-527504 | 200 µg Ab; 10 µg BP | $354.00 | |||
FGF-17 Antibody (B-4): m-IgG1 BP-HRP Bundle | sc-532877 | 200 µg Ab; 20 µg BP | $354.00 | |||
FGF-17 Antibody (B-4) AC | sc-376056 AC | 500 µg/ml, 25% agarose | $416.00 | |||
FGF-17 Antibody (B-4) HRP | sc-376056 HRP | 200 µg/ml | $316.00 | |||
FGF-17 Antibody (B-4) FITC | sc-376056 FITC | 200 µg/ml | $330.00 | |||
FGF-17 Antibody (B-4) PE | sc-376056 PE | 200 µg/ml | $343.00 | |||
FGF-17 Antibody (B-4) Alexa Fluor® 488 | sc-376056 AF488 | 200 µg/ml | $357.00 | |||
FGF-17 Antibody (B-4) Alexa Fluor® 546 | sc-376056 AF546 | 200 µg/ml | $357.00 | |||
FGF-17 Antibody (B-4) Alexa Fluor® 594 | sc-376056 AF594 | 200 µg/ml | $357.00 | |||
FGF-17 Antibody (B-4) Alexa Fluor® 647 | sc-376056 AF647 | 200 µg/ml | $357.00 | |||
FGF-17 Antibody (B-4) Alexa Fluor® 680 | sc-376056 AF680 | 200 µg/ml | $357.00 | |||
FGF-17 Antibody (B-4) Alexa Fluor® 790 | sc-376056 AF790 | 200 µg/ml | $357.00 | |||
FGF-17 (B-4) Neutralizing Peptide | sc-376056 P | 100 µg/0.5 ml | $68.00 |