FAT4 Antibody (165E2K): sc-517614
- FAT4 Antibody (165E2K) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against amino acids 4500-4786 of FAT4 of human origin
- recommended for detection of FAT4 of human origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FAT4 Antibody (165E2K). This work is in progress.
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FAT4 Antibody (165E2K) is a mouse monoclonal IgG1 antibody that detects FAT4 in human samples through western blotting (WB). FAT4, also known as FAT tumor suppressor homolog 4, CDHF14, or CDHR11, is a significant single-pass type I membrane protein composed of 4,981 amino acids and is a member of the protocadherin subfamily of cadherins. FAT4 is predominantly localized to the primary cilia of kidney cells, where FAT4 plays a crucial role in the regulation of planar cell polarity, a process essential for proper tissue organization and development. FAT4′s structure is particularly noteworthy, as FAT4 contains thirty-four cadherin domains, six EGF-like domains, and two laminin G-like domains, which contribute to adhesive properties and interactions with other proteins. These structural features are vital for FAT4′s function in mediating cell-cell adhesion and maintaining cellular architecture, making FAT4 an important player in developmental biology and potential tumor suppression. Anti-FAT4 antibody (165E2K) is an invaluable tool for researchers studying the intricate mechanisms of cell adhesion and signaling pathways in human tissues.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FAT4 Antibody (165E2K) | sc-517614 | 100 µg/ml | $316.00 |