FAS-L Antibody (2.1): sc-33716

FAS-L Antibody (2.1) is a mouse monoclonal IgG1 kappa light chain antibody that detects FAS-L of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Anti-FAS-L antibody (2.1) is available in both conjugated and non-conjugated forms, providing flexibility for various experimental needs. FAS-L, or FAS ligand, plays a crucial role in the immune system by mediating apoptosis, which is essential for maintaining immune homeostasis and eliminating potentially harmful cells, such as those infected by viruses or transformed into cancerous cells. The interaction between FAS-L and its receptor, FAS, initiates a cascade of intracellular signaling that leads to programmed cell death, a process vital for preventing autoimmune diseases and controlling tumor growth. FAS, a cell surface glycoprotein, is part of a larger family of receptors that includes CD40 and tumor necrosis factor receptors, highlighting its importance in immune regulation. The expression of FAS on various lymphoid cell lines indicates its potential as a target for therapeutic interventions aimed at enhancing immune responses against malignancies. FAS-L monoclonal antibody (2.1) enables researchers to explore the dynamics of FAS-FAS-L interactions and their implications in immunological research and therapeutic development.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FAS-L Antibody (2.1) has 10 citations in a variety of scientific publications.

Primary antibodies like Anti-FAS-L Antibody (2.1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FAS-L Antibody (2.1) Specifications

Alternate Product Name: FASLG

Product Clone Name: 2.1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: FAS-L

Epitope Species: human

Product Reactivity/Detection: FAS-L

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 10 citations in various scientific publications

Available Conjugates/Forms for FAS-L Antibody (2.1): FITC: Fluoroscein, PE: Phycoerythrin

The preferred FAS-L antibody is FAS-L Antibody (NOK-1): sc-19681.